Sökning: "susceptibility"

Visar resultat 1 - 5 av 1194 avhandlingar innehållade ordet susceptibility.

  1. 1. Neurotoxic Effects of Nicotine During Neonatal Brain Development : Critical Period and Adult Susceptibility

    Författare :Emma Ankarberg; Per Eriksson; Richard F. Seegal; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Biology; nicotine; neonatal development; behaviour; nicotinic receptors; susceptibility; cholinergic system; paraoxon; PBDE; Biologi; Biology; Biologi;

    Sammanfattning : This thesis examined neurotoxic effects of nicotine exposure during a defined critical period of neonatal brain development in mice.In our environment there are numerous hazardous contaminants that an individual can be exposed to during its entire lifetime. LÄS MER

  2. 2. Susceptibility to chronic liver disease

    Författare :Maria Antonella Burza; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :chronic liver disease; susceptibility; human genetics; NAFLD; ALD; PNPLA3;

    Sammanfattning : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. LÄS MER

  3. 3. Susceptibility genes in conformational diseases

    Författare :Malin von Otter; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Conformational disease; Alzheimer’s disease; Parkinson’s disease; Cataract Protein aggregation; Cellular transport; Oxidative stress; Susceptibility; genes; SNP; Haplotype;

    Sammanfattning : Conformational diseases are characterized by protein misfolding and aggregation in the affected tissue. The aim of this thesis was to find genetic support for mechanisms in common for three prevalent ... LÄS MER

  4. 4. Susceptibility effects in MRI and 1H MRS. The spurious echo artifact and susceptibility measurements

    Författare :Åsa Carlsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; 1H MRS; susceptibility; spurious echo; artifact; artefact;

    Sammanfattning : When performing magnetic resonance (MR) experiments, a strong homogeneous magnetic field is often preferred, especially in clinical applications. However, all objects that are placed in the magnetic field will disturb the field homogeneity and cause local magnetic field gradients. LÄS MER

  5. 5. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease

    Författare :Michael Jewett; Translationell Neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s Disease; α-synuclein; Dopaminergic Neurons; Susceptibility; GSTA4; Vra1; rAAV; 6-OHDA; En1; Linkage analysis; Congenic strains; Axonal swellings; QTL; Risk factors; Neuroprotection; Astrocytes;

    Sammanfattning : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. LÄS MER