Sökning: "orexin-B"

Hittade 3 avhandlingar innehållade ordet orexin-B.

  1. 1. Effects of Orexins, Guanylins and Feeding on Duodenal Bicarbonate Secretion and Enterocyte Intracellular Signaling

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Magnus Wilhelm Bengtsson; Uppsala universitet.; [2008]
    Nyckelord :Physiology; alkaline secretion; carbohydrates; central nervous system; cholinergic stimulation; duodenum; enteric nervous system; enterochromaffin cell; fasting; feeding; glucose; guanylyl cyclase C; humans; hypocretin; intra-arterial; in situ; intracerebroventricular; luminal acid; luzindole; orexin-B; SB-334867; Fysiologi;

    Sammanfattning : The duodenal epithelium secretes bicarbonate ions and this is regarded as the primary defence mechanism against the acid discharged from the stomach. For an efficient protection, the duodenum must also function as a sensory organ identifying luminal factors. LÄS MER

  2. 2. Orexin Receptors in Recombinant CHO Cells Signaling to Short- and Long-Term Cell Responses

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Sylwia Ammoun; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; orexins; cell signaling; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi;

    Sammanfattning : Recently discovered neuropeptides orexins (orexin-A and -B) act as endogenous ligands for G-protein-coupled receptors called OX1 and OX2 receptors. Our previous studies have established model systems for investigation of the pharmacology and signaling of these receptors in recombinant CHO cells. LÄS MER

  3. 3. OX1 Orexin Receptor Signalling to Phospholipases

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Marie Ekholm; Uppsala universitet.; Uppsala universitet.; [2010]
    Nyckelord :orexin; phospholipase; Calcium; cell signalling; G protein coupled receptor; ERK; live-cell imaging; arachidonic acid; diacylglycerol;

    Sammanfattning : The neuropeptides orexin-A and orexin-B were discovered in 1998 and were first described as regulators of feeding behaviour. Later research has shown that they have an important role in the regulation of sleep. Two G protein-coupled receptors, OX1 and OX2 orexin receptors, mediate the cellular responses to orexins. LÄS MER