Sökning: "Biology with specialization in Environmental Toxicology"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Biology with specialization in Environmental Toxicology.
1. Developmental exposure to mixtures of environmental pollutants : Studies on metabolism, developmental processes, and reproductive organs in zebrafish and chicken embryos
Sammanfattning : Humans and wildlife are continuously exposed to mixtures of environmental pollutants. Mixture toxicity can be challenging to predict due to interactions between chemicals and thus whole-mixture approaches are crucial in toxicology. LÄS MER
2. In Vitro Studies of Adrenocorticolytic DDT Metabolites, with Special Focus on 3-methylsulfonyl-DDE
Sammanfattning : The DDT metabolite 3-methylsulfonyl-DDE (3-MeSO2-DDE) is bioactivated by cytochrome P450 11B1 (CYP11B1) in the adrenal cortex of mice and forms irreversibly bound protein adducts, reduces glucocorticoid secretion, and induces cell death selectively in cortisol-producing adrenocortical cells. 3-MeSO2-DDE has therefore been proposed as a lead compound for an improved adrenocortical carcinoma (ACC) therapy. LÄS MER
3. Pheromonal Mediated Behaviour and Endocrine Responses in Salmonids : The impact of Cypermethrin, Copper, and Glyphosate
Sammanfattning : The effects of cypermethrin, copper and glyphosate on the endocrine system and subsequent response to female pheromones were investigated in mature male brown trout (Salmo trutta) parr. Responses measured were the amount of strippable milt, blood plasma levels of both an androgen (11-ketotestosterone (11-KT)) and a progestin (17α,20β-dihydroxy-4-pregnen-3-one (17,20b-P)), and behavioural changes. LÄS MER
Sammanfattning : In the 1950s the otter started to decline in numbers and distribution in Sweden and other parts of Europe. In 1972 a game law came into force, listing otter as a species that if found dead should be reported and sent to the authorities. The numbers of dead otters reported from different areas indicate population status and distribution. LÄS MER
5. Developmental Neurotoxicity of Environmental Pollutants : Effects on neuronal protein markers after neonatal exposure
Sammanfattning : This thesis focused on investigations of the developmental neurotoxic effects of bisphenol A (BPA) or perfluorohexane sulfonate (PFHxS), after a single neonatal exposure, during a critical period of the brain development in mice.BPA is a well-known industrial chemical used in the production of polymer products and PFHxS is used as an industrial additive as a surfactant. LÄS MER