Sökning: "nicotinic receptors"
Visar resultat 1 - 5 av 66 avhandlingar innehållade orden nicotinic receptors.
1. Nicotinic and muscarinic receptors in Alzheimer's disease : studies of receptor subtype impairments and modulation by cholinesterase inhibitors and nicotinic agonists
Sammanfattning : .... LÄS MER
2. Nicotinic receptors in the central nervous system : methodological and functional aspects
Sammanfattning : .... LÄS MER
3. Evolution of acetylcholine receptors and study of the anatomy of the mouse brain reward system
Sammanfattning : This thesis work is divided in two parts. In the first part, I make use of the transgenic TRPV1-Cre mouse line as a tool to investigate the midbrain ventral tegmental area (VTA). LÄS MER
4. Development of nicotinic receptor ligands for positron emission tomography - from in vitro to in vivo : Binding studies of neuronal nicotinic acetylcholine receptors using different ³H-, ¹1C- and `6Br - labeled ligands
Sammanfattning : Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in central processes, such as cognitive functionand memory, and play a critical role in neuropathological changes in Alzheimer's disease (AD). The in vivocharacterization of nAChRs by positron emission tomography (PET) may increase our understanding of thefunctional implications of these receptors in AD and their early changes during this disease. LÄS MER
5. Neurotoxic Effects of Nicotine During Neonatal Brain Development : Critical Period and Adult Susceptibility
Sammanfattning : This thesis examined neurotoxic effects of nicotine exposure during a defined critical period of neonatal brain development in mice.In our environment there are numerous hazardous contaminants that an individual can be exposed to during its entire lifetime. LÄS MER