Sökning: "luminal acid"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden luminal acid.

  1. 1. Aspects on luminal nitric oxide in relation to oesophageal acid exposure and mucosal integrity

    Författare :Mogens Bove; Göteborgs universitet; []
    Nyckelord :nitric oxide; nitric oxide synthase; acid; gastro-esophageal reflux disease; membrane potentials; saliva; nitrate; blood flow; ferret; histopathology;

    Sammanfattning : Nitric oxide (NO) exerts important neuromuscular control of the oesophagus, but little is known about the sources and effects of the NO present in the distal oesophageal lumen. These questions were presently addressed in both human and animal experiments. LÄS MER

  3. 2. Gastric gland luminal pressure and mucosal protection : An in vivo study in the anesthetized rat

    Författare :Ingrid Synnerstad; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; acid secretion; bicarbonate; epithelial cell surface pH; gastric gland; muscularismucosa; micropuncture; mucosal blood flow; mucus gel thickness; omeprazole; permeability; prostaglandins; ranitidine; rat; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : The driving force for creation of channels in gastric mucus, for acid and pepsin transport, ismost probably the hydrostatic pressure generated within the gastric gland lumen. The aim ofthis study was to investigate the origin and regulation of the glandular pressure. LÄS MER

  4. 3. Acid transport through gastric mucus : A study in vivo in rats and mice

    Författare :Mia Phillipson; Lena Holm; Henrik Sjövall; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; gastric acid; pH-sensitive microelectrode; mucus; mucosal blood flow; nitric oxide; intravital microscopy; laser Doppler flowmetry; Fysiologi; Physiology; Fysiologi; Physiology; fysiologi;

    Sammanfattning : The gastric mucosa is frequently exposed to endogenously secreted hydrochloric acid of high acidity. Gastric mucosal defense mechanisms are arranged at different levels of the gastric mucosa and must work in unison to maintain its integrity. LÄS MER

  5. 4. Effects of Orexins, Guanylins and Feeding on Duodenal Bicarbonate Secretion and Enterocyte Intracellular Signaling

    Författare :Magnus Wilhelm Bengtsson; Gunnar Flemström; Olof Nylander; Karl E. O. Åkerman; Per M. Hellström; Uppsala universitet; []
    Nyckelord :Physiology; alkaline secretion; carbohydrates; central nervous system; cholinergic stimulation; duodenum; enteric nervous system; enterochromaffin cell; fasting; feeding; glucose; guanylyl cyclase C; humans; hypocretin; intra-arterial; in situ; intracerebroventricular; luminal acid; luzindole; orexin-B; SB-334867; Fysiologi;

    Sammanfattning : The duodenal epithelium secretes bicarbonate ions and this is regarded as the primary defence mechanism against the acid discharged from the stomach. For an efficient protection, the duodenum must also function as a sensory organ identifying luminal factors. LÄS MER

  7. 5. Phenotype and function of intestinal CD103+ dendritic cells

    Författare :Elin Jaensson Gyllenbäck; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD103; dendritic cell; CX3CR1; small intestine; MLN; CCR9; Vitamin A; retinoic acid;

    Sammanfattning : Mucosal tissues such as the intestine present an enormous surface area to the outside environment and are continually exposed to foreign antigens in food and microflora. Thus, the intestinal mucosa must must remain tolerant to these innocuous antigens while at same time be able to mount effective immune responses to pathogens. LÄS MER