Sökning: "brain insulin"

Visar resultat 21 - 25 av 125 avhandlingar innehållade orden brain insulin.

1. 21. Clinical Studies in the Acute Phase of Subarachnoid Haemorrhage

   Författare :Maria Zetterling; Elisabeth Ronne Engström; Ola Nilsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid haemorrhage; microdialysis; brain energy metabolism; brain glucose; pyruvate; amino acids; cerebral oedema; ACTH; cortisol; Neurosurgery; Neurokirurgi; Neurosurgery; Neurokirurgi;

   Sammanfattning : Patients admitted in similar clinical condition after spontaneous SAH can develop very different clinical courses. This could depend on the severity of the initial global ischemic brain injury at ictus. LÄS MER

3. 22. Pathophysiological Mechanisms and Diagnostic Markers in Alzheimer’s Disease

   Författare :Joakim Hertze; Klinisk minnesforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; mild cognitive impairment; white matter lesions; brain reserve; blood-brain barrier; angiogenesis; neuroinflammation; neurogranin; YKL-40; VEGF; IGF; ICAM-1; VCAM-1;

   Sammanfattning : Alzheimer’s disease (AD), the most common cause of dementia, is a growing concern. As the life expectancy increases across the globe, the number of affected people is estimated to reach 100 million by 2050. LÄS MER

4. 23. The effects of Nordic berries on cognition and brain function : Connections with gut microbiota composition and cardiometabolic risk markers

   Författare :Fang Huang; Bioteknik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nordic berries; cognition; brain function; gut microbiota; cardiometabolic function;

   Sammanfattning : An aging population is associated with an increased prevalence of cognitive decline and related diseases. Gradual cognitive decline is a natural feature of aging, but may also develop into a more severe loss of cognitive function, manifesting as mild cognitive impairment or severe cognitive disease. LÄS MER

5. 24. Molecular studies of the insulin-like growth factor system in the brain : focus on growth, tumorigenesis and trauma

   Författare :Ann-Christin Sandberg Nordqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :insulin-like growth factors; insulin-like growth factor binding proteins; brain; mRNA; meningioma; glioma; traumatic brain injury; in situ hybridization; Northern blothybridization;

   Sammanfattning : Insulin-like growth factor (IGF) 1 and -2 are synthesized by most tissues of the body and function as autocrine or paracrine agents in a tissue-specific manner. mRNA for IGF-1 and -2, as well as the IGF-binding proteins, are synthesized locally in various regions of the brain. LÄS MER

7. 25. Insulin-antagonistic neurohormonal pathways in the development of insulin resistance and type 2 diabetes

   Författare :Martin Lundqvist; Jan W Eriksson; Niclas Abrahamsson; André van Beek; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucagon; cortisol; ACTH; growth hormone; counter-regulation; clamp; hypoglycemia; hyperglycemia; obesity; type 2 diabetes; inflammation;

   Sammanfattning : According to the current paradigm, the development of type 2 diabetes is driven by insulin resistance and the gradual failure of beta cells to compensate for this by secreting adequate amounts of insulin. Obesity is an important risk factor for type 2 diabetes and is considered to influence disease development primarily by induction of insulin resistance, via mechanisms that have not been fully elucidated. LÄS MER