Sökning: "Jan W Eriksson"
Hittade 3 avhandlingar innehållade orden Jan W Eriksson.
1. Role of nuclear receptors in the regulation of human adipose tissue metabolism
Sammanfattning : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). LÄS MER
2. Insulin-antagonistic neurohormonal pathways in the development of insulin resistance and type 2 diabetes
Sammanfattning : According to the current paradigm, the development of type 2 diabetes is driven by insulin resistance and the gradual failure of beta cells to compensate for this by secreting adequate amounts of insulin. Obesity is an important risk factor for type 2 diabetes and is considered to influence disease development primarily by induction of insulin resistance, via mechanisms that have not been fully elucidated. LÄS MER
3. Identifying risk of type 2 diabetes : epidemiologic perspectives from biomarkers to lifestyle
Sammanfattning : Type 2 diabetes is a significant health problem because of its high prevalence and strong association with cardiovascular morbidity and mortality. An increase of type 2 diabetes is predicted due to increasing obesity and sedentary lifestyle habits. LÄS MER