Sökning: "brain energy metabolism"

Visar resultat 1 - 5 av 57 avhandlingar innehållade orden brain energy metabolism.

  1. 1. Glutamate Turnover and Energy Metabolism in Brain Injury : Clinical and Experimental Studies

    Författare :Carolina Samuelsson; Elisabeth Ronne-Engström; Lars Hillered; Eva Kumlien; Carl-Henrik Nordström; Uppsala universitet; []
    Nyckelord :Neurosciences; glutamate; glutamine; lactate; pyruvate; microdialysis; GLT-1; energy metabolism; intracranial pressure; cerebral perfusion pressure; subarachnoid hemorrhage; ischemia; epilepsy; Neurovetenskap;

    Sammanfattning : During brain activity neurons release the major excitatory transmitter glutamate, which is taken up by astrocytes and converted to glutamine. Glutamine returns to neurons for re-conversion to glutamate. This glutamate-glutamine cycle is energy demanding. LÄS MER

  2. 2. Energy Balance out of Balance after Severe Traumatic Brain Injury

    Författare :Karolina Krakau; Jörgen Borg; Torbjörn Karlsson; Catharina Nygren de Boussard; Folke Hammarqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy expenditure; Traumatic brain injury; Metabolism; Nutrition; Nutrition; Näringslära; Neurosurgery; Neurokirurgi; Intensive care; Intensivvård; Nursing; Omvårdnad; Nutrition; Nutrition; Neurosurgery; Neurokirurgi; Rehabilitation Medicine; Rehabiliteringsmedicin; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård; Omvårdnadsforskning med medicinsk inriktning; Caring Sciences in Medical Sciences;

    Sammanfattning : The overall aim of the research presented here was to expand the knowledge on metabolic course and nutritional outcome in patients with severe traumatic brain injury and to analyze the use and accuracy of different methods of assessment. Study I, a systematic review of 30 articles demonstrated consistent data on increased metabolic rate, of catabolism and of upper gastrointestinal intolerance in the majority of the patients during early post injury period. LÄS MER

  3. 3. Perinatal Energy Substrate Metabolism : Glucose Production and Lipolysis in Pregnant Women and Newborn Infants with Particular Reference to Intrauterine Growth Restriction (IUGR)

    Författare :Barbro Diderholm; Jan Gustafsson; Uwe Ewald; Olle Söder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; Lipolysis; Glucose; Newborn infant; Pregnant women; IUGR; Insulin; Stable isotopes; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Sammanfattning : Glucose is the most important fetal nutrient and the production of this substrate increases in the pregnant woman. In the last trimester the increased insulin resistance directs energy substrates to the fetus. Fetal growth is sometimes disturbed, often without an obvious explanation. LÄS MER

  4. 4. The psycho-metabolic consequences of sleep loss in people

    Författare :Lieve T. van Egmond; Christian Benedict; Veronica Witte; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sleep; nutrition; metabolism; sleep deprivation; sex differences; weight differences; obesity; cognition; mediterranean diet; brain health; social evaluation; night work; occupational performance; emotion; vigilance; energy balance; diet; elderly; Fysiologi; Physiology; Nutrition; Nutrition; Neurology; Neurologi; Psychiatry; Psykiatri; Geriatrics; Geriatrik; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Night work is vital for maintaining our 24/7 society; however, in the long run, it may have adverse health consequences like obesity and Alzheimer’s disease. By performing one of the most extensive experimental in-laboratory studies to date, I sought to investigate how sleep deprivation impacts important features like how a person responds to others and how well a person can sustain attention and wakefulness during simulated night work. LÄS MER

  5. 5. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity

    Författare :Gittan Kollberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Energy metabolism; Mitochondrial Disorders; mtDNA; multiple mtDNA deletions; Alpers-Huttenlocher syndrome; POLG1; GYS1; glycogen synthase; point mutation; Polymerase gamma;

    Sammanfattning : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. LÄS MER