Sökning: "Volume transmission"

Visar resultat 1 - 5 av 129 avhandlingar innehållade orden Volume transmission.

  1. 1. Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides

    Författare :Andreas Toft Sörensen; Experimentell Epilepsi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LTP; synaptic plasticity; synaptic transmission; electrophysiology; Y5 receptor; Y2 receptor; neuropeptide Y NPY ; hippocampus; gene therapy; epilepsy; memory; activity-dependent release; volume transmission;

    Sammanfattning : Intractable seizures and lack of effective antiepileptic drugs (AED) are severe and common conditions affecting many patients with epilepsy. Thus, there is an urgent need to develop new therapies in epilepsy. The search for novel treatments has identified several neuropeptide systems as potential targets for future therapeutic interventions. LÄS MER

  3. 2. The interaction of hydrogen with metallic glass

    Författare :Johan Bylin; Gunnar K. Pálsson; Ralph H. Scheicher; Gabriella Andersson; Astrid Pundt; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metallic glass; hydrogen; thin film; density functional theory; stochastic quenching; molecular dynamics; x-ray diffraction; pair distribution function; neutron reflectometry; volume expansion; elastic hydrogen-hydrogen interaction; dipole force tensor; electronic structure; optical conductivity; resistivity; optical transmission; x-ray photoelectron spectroscopy; thermodynamic driving force; Gibbs free energy; Physics with spec. in Atomic; Molecular and Condensed Matter Physics; Fysik med inriktning mot atom- molekyl- och kondenserande materiens fysik;

    Sammanfattning : Combining theoretical ab initio calculations with high-purity thin film sample synthesis and in situ measurements is a compelling way to bridge the gap in our understanding concerning hydrogen in metallic glasses, which is the primary work of this dissertation thesis. The main emphasis has been on how hydrogen affects the structure of metallic glasses, and how those changes influence not only the electronic properties of the amorphous metals but also their thermal stability. LÄS MER

  4. 3. Tandem optical parametric oscillators using volume Bragg grating spectral control

    Författare :Markus Henriksson; Fredrik Laurell; Hiromasa Ito; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; optical parametric oscillators; mid-infrared; volume Bragg gratings; PPKTP; ZGP; nonlinear optics; narrowband OPO; Physics; Fysik;

    Sammanfattning : This thesis describes research on near degenerate quasi phase-matched opticalparametric oscillators (OPO) where volume Bragg gratings (VBG) are used toproduce narrow oscillation bandwidth. These OPOs are then used to pump a secondOPO to generate mid-infrared radiation. The atmospheric transmission windows in the 3. LÄS MER

  5. 4. Experimental studies on the sources, pathways and targets for volume transmission in the rat brain

    Författare :Anders Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :volume transmission; extracellular space; monoamines; Dl D2 receptors; 5HT2A receptors; nitric oxide; interleukin-1ß; cholecystokinin; galanin;

    Sammanfattning : Volume transmission has been defined as the three-dimensional diffusion or convection of transmitters in the extracellular space (ECS) and cerebrospinal fluid (CSF) over a larger distance than the synaptic cleft. The regional localization of dopamine (DA) nerve terminals and dopamine Dl and D2 receptors in nucleus accumbens were studied in detail using double immuno-labelling. LÄS MER

  7. 5. The Epistle of Jude : Its Text and Transmission

    Författare :Tommy Wasserman; Bibelvetenskap; []
    Nyckelord :HUMANIORA; HUMANITIES; internal evidence; New Testament; external evidence; textual variant; textual commentary; lectionary; minuscule; uncial; amulet; P78; P72; Bodmer Codex; papyrus; textual criticism; literary relationship; 2 Peter; Jude; Bible; Catholic Epistles; papyrology; paleography; codicology; Christianity; Kristendom;

    Sammanfattning : This study treats the textual tradition of the Epistle of Jude. After an introductory survey of earlier text-critical research, the two main purposes of this investigation are formulated: to gather and to analyze the complete textual evidence of the Epistle of Jude. LÄS MER