Sökning: "cholecystokinin"

Visar resultat 1 - 5 av 63 avhandlingar innehållade ordet cholecystokinin.

  1. 1. On Cholecystokinin and Phospholipase A2 in Insulin Secretion - an Experimental Study With Reference to the Development of Diabetes

    Författare :Erik Simonsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin Resistance; Islet; Beta-cell; Insulin Secretion; Ca2 -Dependency; Intracellular Signalling; Phospholipase A2; Cholecystokinin; Non-glucose Secretagogues; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : In view of unsolved issues regarding cellular events underlying the adaptation of insulin secretion to insulin resistance, together with the observation that insulin secretion induced by the gastrointestinal hormone and neuropeptide cholecystokinin (CCK) is not solely explained by phospholipase C-protein kinase C (PLC-PKC) pathway activation, this study aimed at delineate mechanisms responsible for the hyperinsulinemia in insulin resistance, with particular attention paid to the action of glucose vs. non-glucose secretagogues, such as CCK. LÄS MER

  2. 2. The cholecystokinin receptor family : molecular cloning and pharmacological characterization

    Författare :Isabelle Nilsson; Dan Larhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cholecystokinin (CCK) and gastrin are hormones/neurotransmittors of the gastrointestinal tract and central nervous system. The receptors for gastrin and CCK are members of the G protein-coupled receptor family. The aim of this study was to clone and pharmacologically characterize vertebrate and invertebrate CCK receptors and splice variants. LÄS MER

  3. 3. Secretory and anti-inflammatory actions of some gastro-intestinal hormones in salivary glands

    Författare :Hülya Çevik Aras; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :salivary glands; protein secretion; synthesis; inflammation; β-defensins; myeloperoxidase; cholecystokinin; gastrin; melatonin; nitric oxide; nerve stimulation;

    Sammanfattning : Textbooks generally state that the secretory activity of salivary glands is solely regulated by nerves. This view is challenged in the present Thesis, using the parotid gland of the anaesthetized rat as experimental in vivo model. LÄS MER

  4. 4. Liver regeneration : With reference to malnutrition and growth factors

    Författare :Stefan Skullman; Linköpings universitet; []
    Nyckelord :cholecystokinin; energy substrates; epidermal growth factor; insulin-like growth factor I; liver composition; liver regeneration; malnutrition; pancreaticobiliary diversion; protein synthesis; rat; transfonning growth factor alpha; MEDICINE; MEDICIN;

    Sammanfattning : The liver has a unique capacity to regenerate after damage, irrespective of cause. The regulatory mechanisms of this regeneration are not fully known. Liver regeneration· is associated with rapid growth and thereby increased demands for energy and synthesis of new compounds. LÄS MER

  5. 5. The Role of CCK-A and CCK-B Receptors in the Trophic Control of Pancreas and Oxyntic Mucosa in the Rat

    Författare :Anna-Greta Nylander; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; trophic effects; rats; portacaval shunt; oxyntic mucosa; gastrin; Cholecystokinin; enterochromaffin-like ECL cells; CCK-A CCK-B receptor; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Cholecystokinin (CCK) and the related hormone gastrin have been claimed to exert trophic effects in the pancreas and gastrointestinal tract. Two types of receptors for CCK and gastrin are known to exist, the CCK-A and the CCK-B receptor. They differ in their affinty for CCK and gastrin. LÄS MER