Sökning: "Fredrik Lennmyr"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Fredrik Lennmyr.
1. Signal Transduction in Focal Cerebral Ischemia : Experimental Studies on VEGF, MAPK and Src family kinases
Sammanfattning : Cerebral ischemia elicits a wide range of events, including complex activation of various intracellular signaling pathways. This study aims to investigate the expression of vascular endothelial growth factor (VEGF) and the activation pattern of mitogen-activated protein kinases (MAPK) in reponse to focal cerebral ischemia. LÄS MER
2. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies
Sammanfattning : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. LÄS MER
3. Cerebral Perfusion and Metabolism during Experimental Extracorporeal Circulation
Sammanfattning : Neurologic injuries are major causes of mortality and morbidity after cardiac surgery. This thesis aimed to investigate cerebral metabolism and perfusion abnormalities in pigs during hypothermic circulatory arrest, selective antegrade cerebral perfusion (SACP) and extracorporeal circulation following progressive venous stasis. LÄS MER
4. Hyperglycemia in Experimental Cerebral Ischemia
Sammanfattning : Cerebral ischemia is a life-threatening condition associated with a substantial morbidity and mortality. Hyperglycemia, a common coexisting phenomenon in both stroke and cardiac arrest (CA), may further aggravate ischemic brain injury. To date, the therapeutic possibilities are lim-ited and the search for new treatment modalities is warranted. LÄS MER
5. Cerebral Perfusion during Cardiopulmonary Bypass
Sammanfattning : Impaired superior vena cava (SVC) cannula outflow during cardiopulmonary bypass (CPB) is a frequent issue, often manifested by only marginal changes in routine monitoring parameters. Nevertheless, significant impact on cerebral perfusion may result. LÄS MER