Sökning: "Spike protein"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Spike protein.

  1. 1. In silico protein design for the enhancement of protein stability and function

    Författare :David A. Hueting; Per-Olof Syrén; Hjalmar Brismar; Zbynek Prokop; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein Engineering; Ancestral sequence reconstruction; terpene cyclases; SARS-CoV-2; Spike protein; PET; PETase; rational engineering; Proteinteknik; Förfäders sekvensrekonstruktion; Terpencyklas; SARS-CoV-2; Spike protein; PET; PETas; rationell proteinteknik; Kemi; Chemistry;

    Sammanfattning : Enzymes are natures catalysts that increase the rate of a chemical reaction. The increased rate of a reaction is required to be able to sustain life. Despite the huge impact of enzymes, they are not perfect catalysts. LÄS MER

  3. 2. Protein interactions involved in alphavirus assembly

    Författare :Ulrica Skoging Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alphavirus; Semliki Forest Virus; Virus assembly; Capsid Protein; Nucleocapsid; Viral Envelope Proteins;

    Sammanfattning : Viruses have to protect their genomes during transport from the infected to an uninfected host cell. This is achieved by forming a protein shell around the nucleic acid. Virus assembly is a complex process that involves interactions with the viral genome, the viral structural proteins and for enveloped viruses a lipid membrane. LÄS MER

  4. 3. Activation of the spike proteins of alpha- and retroviruses

    Författare :Shang-Rung Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alphavirus; Retrovirus; Fusion protein; electron cryomicroscopy; intermediate structure;

    Sammanfattning : Enveloped viruses like human immunodeficiency virus type 1 (HIV-1) enter cells by fusing their membrane with that of the cell plasma membrane, while others, like influenzavirus and alphavirus enter via uptake into endosomes and fusion with the endosomal membrane. For this they carry spike proteins. LÄS MER

  5. 4. Effects of Vagus Nerve Stimulation and Ketogenic Diet on Quality of Life and Changes in EEG and Sleep

    Författare :Tove Hallböök; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vagus nerve stimulation; neuropsykologi; Neurologi; neurophysiology; neuropsychology; Neurology; Medicin människa och djur ; Medicine human and vertebrates ; behaviour; attention; ketogenic diet; delta power; slow wave sleep; REM; mood; sleep; quality of life; EEG; seizure frequency; spike detection; children; neurofysiologi; Pediatri; epilepsy; Pediatrics;

    Sammanfattning : When anti-epileptic drugs fail, and epilepsy surgery is found unfeasible or ineffective, there remains a group of at least 25% of children with epilepsy in whom seizure control cannot be achieved. Vagus nerve stimulation (VNS) is an adjunctive treatment for medically refractory epilepsy. LÄS MER

  7. 5. The role of the capsid protein in Semliki Forest virus assembly

    Författare :Kerstin Forsell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; RNA encapsidation; NC assembly; virus budding; RNA uncoating;

    Sammanfattning : Enveloped viruses, like the Alphaviruses, encapsidate their genomes into a nucleocapsid (NC) or core structure which is surrounded by a lipid bilayer (envelope) with spike proteins. The alphavirus Semliki Forest virus (SFV), is an RNA virus with a genomic 42 S RNA of positive polarity. LÄS MER