Sökning: "virus budding"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden virus budding.

  1. 1. Assembly and entry mechanisms of Semliki Forest virus

    Författare :Bernd Uwe Barth; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; virus assembly; protein oligomerization; virus budding;

    Sammanfattning : The genomes of enveloped viruses are packaged into a core or nucleocapsid (NC) which is surrounded by a lipid membrane with spike proteins. These viruses mature by budding at a membrane of the host cell, usually the plasma membrane (PM), and penetrate into new ones by a virus-host membrane fusion event. LÄS MER

  3. 2. Envelopment of retrovirus and vaccinia virus

    Författare :Kristina Wallengren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Retrovirus; Vaccinia virus; Envelopment; Host proteins; Gag-particles; IMV A17L.;

    Sammanfattning : This thesis describes envelopment of retrovirus and vaccinia virus. Retrovirus envelopment, i.e. budding, occurs from the plasma membrane (PM) of infected cells in an environment that is abundant with cellular proteins. LÄS MER

  4. 3. The role of the capsid protein in Semliki Forest virus assembly

    Författare :Kerstin Forsell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; RNA encapsidation; NC assembly; virus budding; RNA uncoating;

    Sammanfattning : Enveloped viruses, like the Alphaviruses, encapsidate their genomes into a nucleocapsid (NC) or core structure which is surrounded by a lipid bilayer (envelope) with spike proteins. The alphavirus Semliki Forest virus (SFV), is an RNA virus with a genomic 42 S RNA of positive polarity. LÄS MER

  5. 4. Incorporation of cellular proteins into enveloped virus particles

    Författare :Maria Hammarstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MLV; HIV-1; assembly; protein sorting; HfIV-6A; autoimmunity; MS;

    Sammanfattning : This thesis work aimed to investigate the assembly and budding of enveloped virus particles with focus on the fate of cellular proteins, present in or near the plasma membrane (PM) where the budding occurs. It was previously shown that compact viruses, like alphaviruses, with a covering outer protein coat, did not contain any cellular proteins in the envelope. LÄS MER

  7. 5. Assembly of semliki forest and influenza A viruses

    Författare :Hongxing Zhao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki forest virus; influenza virus; virus budding.;

    Sammanfattning : Enveloped viruses contain an external lipid membrane with spikes surrounding their nucleocapsid (NC). The envelope is acquired at a late stage of virus assembly by budding of the NC through a virus-modified host membrane. LÄS MER