Sökning: "electron cryomicroscopy"

Hittade 4 avhandlingar innehållade orden electron cryomicroscopy.

  1. 1. P-type ATPases studied by electron microscopy and two-dimensional crystallization

    Författare :Kenneth Yijing Xian; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :electron microscopy; ion transport; membrane protein; P-type ATPase; two-dimensional crystallization;

    Sammanfattning : Electron microscopy and two-dimensional crystallography have been used to study the molecular structures of the porcine renal Na+,K+-ATPase and the porcine gastric H+,K+-ATPase. In addition, morphological changes have been observed with electron cryomicroscopy from tubulovesicles in porcine gastric mucosae. LÄS MER

  3. 2. Activation of the spike proteins of alpha- and retroviruses

    Författare :Shang-Rung Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Alphavirus; Retrovirus; Fusion protein; electron cryomicroscopy; intermediate structure;

    Sammanfattning : Enveloped viruses like human immunodeficiency virus type 1 (HIV-1) enter cells by fusing their membrane with that of the cell plasma membrane, while others, like influenzavirus and alphavirus enter via uptake into endosomes and fusion with the endosomal membrane. For this they carry spike proteins. LÄS MER

  4. 3. Protein adaptability involved in self-assembled icosahedral capsids

    Författare :Josefina Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :BK virus; lumazine synthase; virus-like particle; electron cryomicroscopy; quasiequivalence; assembly;

    Sammanfattning : Interactions between viral coat proteins determine the size and shape of the virus capsid. Therefore, the plain closed shell of a spherical virus provides an excellent resource for studying and testing protein-protein interactions so as to reveal the properties that lead to symmetrical capsids or other shapes. LÄS MER

  5. 4. Antimicrobial Peptide Interactions with Phospholipid Membranes : Effects of Peptide and Lipid Composition on Membrane Adsorption and Disruption

    Författare :Adam A Strömstedt; Martin Malmsten; Georges Belfort; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; peptide; adsorption; liposome; membrane; melittin; cholesterol; tryptophan; phospholipid; bilayer; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Sammanfattning : The interactions between antimicrobial peptides and phospholipid membranes were investigated, in terms of lipid headgroup variations and the role of cholesterol, as well as peptide composition and structure. Also strategies for increasing proteolytic stability were evaluated. LÄS MER