Sökning: "STEM"

Visar resultat 1 - 5 av 1466 avhandlingar innehållade ordet STEM.

  1. 1. Stem cell function and organ development analysis of Lhx2 function in hematopoietic stem cells and eye development

    Detta är en avhandling från Umeå : Umeå university

    Författare :Lina Dahl; Umeå universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lhx2; hematopoietic system; hematopoietic stem cell; progenitor; embryonic stem cell; embryoid body; eye development; forebrain; eye field transcription factor; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Molecular medicine genetics and pathology ; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Molekylär medicin genetik och patologi ; molekylär medicin genetik och patologi ; Molecular Medicine;

    Sammanfattning : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. LÄS MER

  2. 2. Human embryonic stem cells for bone engineering applications

    Detta är en avhandling från Umeå : Umeå university

    Författare :Giuseppe Maria de Peppo; Göteborgs universitet.; Gothenburg University.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human skeleton; bone; bone defects; bone regeneration; regenerative medicine; tissue engineering; biomaterials; scaffold; biocoral; titanium; osseointegration bioreactor; human stem cells; embryonic stem cells; mesenchymal stem cells; embryonic-derived progenitors; osteogenic differentiation; mineralization; immune response; in vitro; in vivo;

    Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER

  3. 3. Stem cell based therapy of malignant brain tumors

    Detta är en avhandling från Avd för Neurokirurgi, Inst för kliniska vetenskaper, Medicinska fakulteten, Lunds Universitet

    Författare :Daniel Bexell; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; pericyte; mesenchymal stem cell; neuroblast; subventricular zone; cancer stem cell; rat; glioma; cancer;

    Sammanfattning : Malignant brain tumor is a highly invasive and vascularized cancer. Current forms of therapy are not curative and can, at best, prolong survival for patients with this disease. The mean survival is only around 15 months. LÄS MER

  4. 4. Regulation of Hematopoietic Stem Cells

    Detta är en avhandling från Division of Molecular Medicine and Gene Therapy

    Författare :Emma Rörby; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; hematopoietic stem cells; hematopoietic stem cell expansion; cord blood; transforming growth factor beta; Smad signaling; pigment epithelium derived factor; CD9;

    Sammanfattning : This thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. LÄS MER

  5. 5. Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells

    Detta är en avhandling från Lund University, Faculty of Medicine, Institution of Laboratory Medicine, Division of Molecular Medicine and Gene Therapy

    Författare :Roger Rönn; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hematopoietic stem cells; pluripotent stem cells; embryonic development.; in vitro differentiation;

    Sammanfattning : There is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. LÄS MER