Sökning: "embryoid body"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden embryoid body.

  1. 1. VEGFR-2 in Endothelial Differentiation and Vascular Organization

    Författare :Dan Edholm; Lena Claesson-Welsh; Xiujuan Li; Victoria Bautch; Uppsala universitet; []
    Nyckelord :Molecular medicine; Embryonic stem; VEGFR-2; Flk1; KDR; VEGF; vasculogenesis; angiogenesis; embryoid body; Molekylärmedicin;

    Sammanfattning : The cardiovascular system is the first functional organ to develop during embryogenesis. As the embryo reaches above a certain size, passive diffusion of gases and nutrients is no longer compatible with efficient growth. LÄS MER

  3. 2. Modulation of Angiogenesis by Laminins and Heparan Sulfate

    Författare :Lars Jakobsson; Lena Claesson-Welsh; Johan Kreuger; Elisabetta Dejana; Uppsala universitet; []
    Nyckelord :Molecular medicine; Embryonic stem; heparan sulfate; laminin; basement membrane; VEGFR-2; VEGF; endothelial cell; signaling; angiogenesis; vasculogenesis; embryoid body; Molekylärmedicin;

    Sammanfattning : Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. LÄS MER

  4. 3. Hypoxia-inducible factors (HIFs) and biological responses, in hypoxia, inflammation and embryonic vascular development

    Författare :Maria Hägg; Göteborgs universitet; []
    Nyckelord :Embryonic stem cell; embryoid body; HIF-1a; hypoxia; VEGF; angiogenesis; vasculogenesis; peritoneal dialysis;

    Sammanfattning : ABSTRACT Low oxygen tension (hypoxia) is a major inducer of neovascularisation and evidence emerging has indicated that oxygen tension and hypoxia-inducible factors (HIFs), a family of oxygen-regulated heterodimeric transcription factors, may play important roles in vascular and hematopoietic development. This thesis has focused on studying molecular and cellular mechanisms, by which cells and organisms sense changes in oxygen tension, and how this signal is transduced by HIFs into downstream signalling. LÄS MER

  5. 4. Stem cell function and organ development : analysis of Lhx2 function in hematopoietic stem cells and eye development

    Författare :Lina Dahl; Leif Carlsson; Jan-Ingvar Jönsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lhx2; hematopoietic system; hematopoietic stem cell; progenitor; embryonic stem cell; embryoid body; eye development; forebrain; eye field transcription factor; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Sammanfattning : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. LÄS MER

  7. 5. Angiogenic growth factors : mechanism of action and function in vascular development

    Författare :Charlotte Rolny; Andrius Kazlauskas; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; PDGF-BB; VEGF; angiogenesis; hypoxia; migration; heparin; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molecular Medicine; molekylär medicin genetik och patologi ;

    Sammanfattning : The mature vascular system is composed of a network of blood vessels organized into arteries, capillaries, and veins. The vessels are composed of endothelial cells surrounded by smooth muscle cells and embedded in a specialized basement membrane. LÄS MER