Sökning: "Stem cell donation"

Hittade 4 avhandlingar innehållade orden Stem cell donation.

  1. 1. Allogeneic stem cell transplantation : patients’ and sibling donors’ perspectives

    Författare :Annika M Kisch; Malmö högskola; []
    Nyckelord :Allogeneic haematopoietic stem cell transplantation; Confidentiality; Information and care model; Quality of life; Perspectives; Sibling donor; Stem cell donation;

    Sammanfattning : Allogeneic haematopoietic stem cell transplantation (hereafter HSCT) is an established treatment which offers a potential cure for a variety of diseases, mainly haematological malignancies. However, the treatment is also associated with significant risks of acute complications and late side effects, including mortality. LÄS MER

  3. 2. Potential Hazards for Haematopoietic Stem Cell Donors

    Författare :Simon Pahnke; Hans Hägglund; Gunnar Larfors; Nina Worel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cell donor; stem cell transplantation; cancer; haematology; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The aim of this thesis has been to increase our knowledge about the allogeneic stem cell donation procedure and the associated risks for stem cell donors.  In a first study (paper I), we described the donation procedure and short-term side effects of 1957 donors included in the Nordic Register of Haematopoietic Stem Cell Donors. LÄS MER

  4. 3. Human Embryonic Stem Cells: Directed Differentiation into Posterior Foregut Endoderm and a Functional Assay for Definitive Endoderm

    Författare :Martina Johannesson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : A decade has passed since the first human embryonic stem cell (hESC) line was established, providing immense hope in curing diseases by cell replacement therapy. For instance, in the pancreas, the insulin-producing β-cells are damaged in diabetes patients, and a successful replacement of those cells could provide a cure. LÄS MER

  5. 4. Anti-tumour effect in solid tumours, tolerance and immune reconstition after allogeneic haematopoietic stem cell transplantation

    Författare :Patrik Hentschke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Both in haematological malignancies and in disseminated solid tumours, re-occurrence of the underlying disease is the main complication. Allogeneic haematopoietic stem cell transplantation (HSCT) increases the chance of cure compared to only chemotherapy in haematological malignancies, but adds the risk of immunological complications such as graft-versus-host disease (GVHD) and severe infections. LÄS MER