Sökning: "osteogenic differentiation"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden osteogenic differentiation.

  1. 1. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation

    Författare :Cecilia Granéli; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; Mesenchymal stromal cells; Osteogenic differentiation; Adipogenic differentiation; Bone regeneration; Inflammation; Monocytes; Infection; Bacterial membrane vesicles; Compromised bone healing; Cell surface proteins; CD-markers; Osseointegration; Regenerative medicine;

    Sammanfattning : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. LÄS MER

  2. 2. Differentiation of Human Dermal Fibroblasts and Applications in Tissue Engineering

    Författare :Pehr Sommar; Gunnar Kratz; Thomas Hansson; Anders Lindahl; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue Engineering; Human Dermal Fibroblasts; Differentiation; Adipogenesis; Chondrogenesis; Endotheliogenesis; Osteogenesis; Plastic surgery; Plastikkirurgi;

    Sammanfattning : Tissue engineering applies principles of biology and engineering to the development of functional substitutes for damaged or lost tissues. Tools for the neo-generation of tissue in tissue engineering research include cells, biomaterials and soluble factors. LÄS MER

  3. 3. Derivation, Characterization and Differentiation of Feeder-Free Human Embryonic Stem Cells

    Författare :Narmin Bigdeli; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Embryonic Stem Cells; Differentiation;

    Sammanfattning : Human embryonic stem cells (hESCs) are pluripotent cells with self-renewal ability, derived from the inner cell mass of a human blastocyst. They have the remarkable potential to develop into different cell types and can thus be used to regenerate and restore damaged tissues and organs in the entire body. LÄS MER

  4. 4. Regenerative effects of mesenchymal stem cell-derived exosomes

    Författare :Xiaoqin Wang; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aging; cell adhesion; cell-material interaction; exosomes; extracellular vesicles; mesenchymal stem cells; osteogenic differentiation; proliferation; regeneration; titanium;

    Sammanfattning : Mesenchymal stem cells (MSCs) play pivotal roles for bone regeneration by virtue of their osteogenic differentiation ability and immunomodulatory capacity. Recently, secretion of exosomes/extracellular vesicles (EVs) has been suggested as a new mechanism of MSC-based therapy. LÄS MER

  5. 5. Human embryonic stem cells for bone engineering applications

    Författare :Giuseppe Maria de Peppo; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human skeleton; bone; bone defects; bone regeneration; regenerative medicine; tissue engineering; biomaterials; scaffold; biocoral; titanium; osseointegration bioreactor; human stem cells; embryonic stem cells; mesenchymal stem cells; embryonic-derived progenitors; osteogenic differentiation; mineralization; immune response; in vitro; in vivo;

    Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER