Sökning: "bone defects"

Visar resultat 1 - 5 av 89 avhandlingar innehållade orden bone defects.

  1. 1. Bone Healing after implantation of bone substitute materials. Experimental studies in estrogen deficiency

    Författare :Sven Öberg; Jan Rosenquist; Ulf Lekholm; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bone grafts; hydroxyapatite; estrogen deficiency; demineralised bone; bone formation; AAA bone; bone defect; titanium implants; resonance frequency analysis.; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

    Sammanfattning : Bone formation and bone healing were studied in the mandible, tibia and skull bones in adult, healthy and estrogen deficient rabbits implanted with different bone substitutes.In the first study an evaluation of the differences in bone regeneration in and around solid (Alveograf *) and porous hydroxyapatite (Interpore 200*) was undertaken. LÄS MER

  2. 2. Human embryonic stem cells for bone engineering applications

    Författare :Giuseppe Maria de Peppo; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human skeleton; bone; bone defects; bone regeneration; regenerative medicine; tissue engineering; biomaterials; scaffold; biocoral; titanium; osseointegration bioreactor; human stem cells; embryonic stem cells; mesenchymal stem cells; embryonic-derived progenitors; osteogenic differentiation; mineralization; immune response; in vitro; in vivo;

    Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER

  3. 3. Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials

    Författare :Ibrahim Elgali; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative medicine; biomaterials; bone substitute; calcium phosphate; guided bone regeneration; membrane; strontium; bone defect; bone remodeling; inflammation; cytokines; chemokines; growth factors; gene expression; histomorphometry; in vivo;

    Sammanfattning : The mechanisms of guided bone regeneration (GBR) and bone healing with calcium phosphate (CaP) bone substitutes are not fully understood. The major aim of this thesis was to determine the relationship between the bone formation in bone defects and the cellular distribution and activities in association with CaP materials and/or with GBR membrane. LÄS MER

  4. 4. Biomaterials for Promoting Self-Healing of Bone Tissue

    Författare :Sonya Piskounova; Jöns Hilborn; Tim Bowden; Simon Cool; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; Osseointegration; implant coating; hyaluronan hydrogel; bone morphogenetic protein-2; hydroxyapatite; bone; delivery system; injectable; mixing; radioactive labeling; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Sammanfattning : The present work addresses poor bone/implant integration and severe bone defects. In both conditions external stimuli is required for new bone to form. LÄS MER

  5. 5. Craniofacial bone reconstruction with Bone Morphogenetic Protein-2

    Författare :Ann-Charlott Docherty Skogh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; bone morphogenetic protein;

    Sammanfattning : Bone defects in the craniofacial area are a clinical challenge and can be the result of trauma, tumour resection or congenital malformations. The golden standard for reconstruction is autologous bone grafts, but bone may not always be readily available and donor-site morbidity might follow. LÄS MER