Sökning: "RNA-protein interactions"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden RNA-protein interactions.
1. RNA-protein interactions in the bacteriophage MS2
Sammanfattning : The bacteriophage MS2 coat protein interacts specifically with a 19 nucleotide long hairpin formed within the viral RNA genome. In the current work the structural details of this interaction have been examined using X-ray crystallography of complexes where the RNA hairpin sequence has been varied. LÄS MER
2. Post-Transcriptional Regulation of the Murine Inducible Nitric Oxide Synthase Gene
Sammanfattning : Large amounts of nitric oxide (NO) are produced by the inducible nitric oxide synthase (iNOS) upon inflammatory stimuli. NO is a multifaceted molecule, which may have beneficial effects as an antimicrobial agent in the immune defense, or cytotoxic effects in chronic inflammations, manifested as e.g. arthritis and asthma. LÄS MER
3. Immuno-affinity interactions in sample preparation and analysis
Sammanfattning : Immuno-affinity interactions (antibody-antigen) belong, together with enzyme-inhibitor/substrate/coenzyme; oligosaccharide-lectin; DNA/RNA-protein interactions etc, to the class of bio-recognition. Immuno-affinity is widely used for analysis in immunoassays with numerous applications in a variety fields (i.e. LÄS MER
4. Dissection of virus-host cell interactions in the early response to infection
Sammanfattning : Stress granules (SG) are dynamic RNA/protein assemblies in the cytoplasm of the cell, formed under conditions of oxidative stress, heat shock or viral infections. These stress conditions trigger a sudden translational arrest, leading to a rapid switch of translation from housekeeping genes to stress-related factors. LÄS MER
5. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element
Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER