Sökning: "Pancreatic islets"

Visar resultat 41 - 45 av 236 avhandlingar innehållade orden Pancreatic islets.

  1. 41. Pitfalls in β-cell ion imaging with fluorescent indicators and their use for real-time detection of somatostatin secretion

    Författare :Mingyu Yang; Anders Tengholm; Enming Zhang; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-cells; cytoplasmic Ca²⁺; cytoplasmic pH; fluorescent indicators; pancreatic islets; R-GECO1; somatostatin; type 2 diabetes; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Fluorescent ion indicators have become indispensable tools in cell physiology. Dye indicators can easily be loaded into most types of cells, while genetically encoded indicators are advantageous in allowing specific cellular or subcellular targeting. LÄS MER

  3. 42. Modulation of the Immune Response in Concordant Xenotransplantation

    Författare :Adam Bersztel; Gunnar Tufveson; Michael Olausson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Antibodies; blood transfusions; heart; pancreatic islets; tolerance; xenotransplantation; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Xenotransplantation, i.e. transplantation between different species, could be a possible solution to the present shortage of organ donors. The immunological response to a xenograft is strong and difficult to suppress. LÄS MER

  4. 43. Characterization of the Pancreas in Type 1 and Type 2 Diabetes

    Författare :Marcus Lundberg; Oskar Skog; Olle Korsgren; Martha Campbell-Thompson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Type 2 diabetes; HbA1c; interferon-stimulated genes; parasympathetic; axon; cellular stress; islets; exocrine; immunology; leucocytes; inflammation; human; pancreas; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Immunologi; Immunology; Patologi; Pathology;

    Sammanfattning : Diabetes is recognized by hyperglycaemia and polyuria. Complications, reduced quality of life and staggering health-care costs are all derived from the disease. Two subclasses of diabetes are Type 1 diabetes (T1D) and Type 2 diabetes (T2D). LÄS MER

  5. 44. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines

    Författare :Annika K. Andersson; Stellan Sandler; Nils Welsh; Décio L. Eizirik; Nils Billestrup; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; β-cell; Cyclooxygenase; Cytokine; Diabetes; IFN-γ; IL-1β; iNOS; Insulin; Melatonin; Nitric oxide; Pancreatic islets; Phospholipase D; Prostaglandin E2; Streptozotocin; Cellbiologi; Cell biology; Cellbiologi;

    Sammanfattning : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. LÄS MER

  7. 45. Effects of glucose and sulfonylureas on sodium in pancreatic islets

    Författare :Liaquat Ali; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER