Sökning: "interferon-stimulated genes"

Hittade 5 avhandlingar innehållade orden interferon-stimulated genes.

  1. 1. Characterization of the Pancreas in Type 1 and Type 2 Diabetes

    Författare :Marcus Lundberg; Oskar Skog; Olle Korsgren; Martha Campbell-Thompson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Type 2 diabetes; HbA1c; interferon-stimulated genes; parasympathetic; axon; cellular stress; islets; exocrine; immunology; leucocytes; inflammation; human; pancreas; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Immunologi; Immunology; Patologi; Pathology;

    Sammanfattning : Diabetes is recognized by hyperglycaemia and polyuria. Complications, reduced quality of life and staggering health-care costs are all derived from the disease. Two subclasses of diabetes are Type 1 diabetes (T1D) and Type 2 diabetes (T2D). LÄS MER

  3. 2. Mechanisms of multicellular drug resistance and novel approaches for targeted therapy in cancer

    Författare :Elin Edsbäcker; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dysregulated gene expression, due to genetic and epigenetic aberrations, as well as cancer cell-stroma interactions underlie both tumorigenesis and resistance to anti-cancer therapy. Although governed by common mechanisms, these features are unique to each individual tumor and therefore a personalized treatment regimen needs to be composed for each patient. LÄS MER

  4. 3. On the immune response in porcine enteric diseases : with special reference to swine dysentery, proliferative enteropathy and PMWS

    Författare :Märit Andersson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Enteric infectious diseases are a common problem worldwide among pigs. It is important to gain a better knowledge about the pathogeneses of the diseases and the local immune response, in which the intestine has a very important role. LÄS MER

  5. 4. The role of non-coding single-stranded oligonucleotides on Respiratory syncytial virus infection

    Författare :Sandra Axberg Pålsson; Anna-Lena Spetz; Annika Karlsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Respiratory syncytial virus RSV ; single-stranded oligonucleotide ssON ; small non-coding RNA sncRNA ; nucleolin; virus infection; antiviral; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Respiratory syncytial virus (RSV) is an enveloped RNA virus of the Pneumoviridae family. RSV is reported to infect host cells by receptor-mediated endocytosis, also called clathrin-dependent endocytosis. Many reports indicate that the virus utilizes the host receptor nucleolin for entry. LÄS MER

  7. 5. The role of the type I interferons and viperin during neurotropic flavivirus infection

    Författare :Richard Lindqvist; Anna Överby Wernstedt; Daniel Ruzek; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TBEV; Flavivirus; Interferon; Neurotropic; Viperin;

    Sammanfattning : Flaviviruses are globally distributed pathogens that cause millions of human infections annually. One of the most detrimental outcomes of flavivirus infection is encephalitis, which is caused by neurotropic flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), and Tick-borne encephalitis virus (TBEV). LÄS MER