Sökning: "Pär Stattin"

Visar resultat 6 - 10 av 15 avhandlingar innehållade orden Pär Stattin.

  1. 6. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

    Författare :Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

    Sammanfattning : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. LÄS MER

  3. 7. Endogenous hormones in the etiology of ovarian and endometrial cancers

    Författare :Annekatrin Lukanova; Eva Lundin; Pär Stattin; Rudolf Kaaks; Susan E. Hankinson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; ovarian cancer; endometrial cancer; sex-steroid hormones; sex-hormone binding globulin; insulin-like growth factor-I; insulin-like growth factor bidning proteins; C-peptide; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; epidemiologi; Epidemiology;

    Sammanfattning : The main purpose of this thesis was to examine the relationship of pre-diagnostic circulating levels of sex-steroids (androgens and estrogens), sex hormone binding globuline (SHBG), insulin-like growth factor-I (IGF-I), IGF binding proteins (BP) and C-peptide (as a marker of pancreatic insulin secretion) with risk of ovarian and endometrial cancer. Additionally, the interrelationships of body mass index (BMI), sex-steroids, IGF-I and IGFBP-3 were examined. LÄS MER

  4. 8. Early effects of castration therapy in non-malignant and malignant prostate tissue

    Författare :Nina Ohlson; Pernilla Wikström; Anders Bergh; Pär Stattin; Marja Nevalainen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; human biopsies; androgen ablation; stroma; epithelium; micro-dissection; PSA; IGF-1; IGF-R1; AR; Pathology; Patologi;

    Sammanfattning : Early Effects of Castration Therapy in Non-malignant and Malignant Prostate Tissue BACKGROUND. Androgen ablation, the standard treatment for advanced prostate cancer, results in increased apoptosis, decreased cell proliferation and subsequent involution of the prostate gland. LÄS MER

  5. 9. Trends in Prostate Cancer Mortality

    Författare :Andri Wilberg Orrason; Pär Stattin; Alberto Briganti; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; mortality; survival; death certificate; adjudication; lifetime risk; diagnosis; life expectancy; Urologi; Urology; Epidemiologi; Epidemiology; Cancer Epidemiology; Cancerepidemiologi;

    Sammanfattning : In the early 20th century, cancer of the prostate was considered a rare and deadly disease with little to no possibility of cure. Since then, prostate cancer management has improved substantially with earlier detection, hormonal therapy, surgery and radiotherapy of the prostate. LÄS MER

  7. 10. Metabolic factors and cancer risk : prospective studies on prostate cancer, colorectal cancer, and cancer overall

    Författare :Tanja Stocks; Pär Stattin; Håkan Jonsson; Annie Lukanova; Jaap Seidell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology and andrology; Urologi och andrologi; epidemiologi; Epidemiology;

    Sammanfattning : Background: A large number of prospective studies have shown that overweight and diabetes are related to an increased risk of many cancers, including colorectal cancer. In contrast, diabetes has been related to a decreased risk of prostate cancer, and overweight has been related to an increased risk of fatal, but not of incident, prostate cancer. LÄS MER