Sökning: "PSA"

Visar resultat 1 - 5 av 126 avhandlingar innehållade ordet PSA.

  1. 1. Assessments of PSA Forms and hK2 as Very Early Predictors of Prostate Cancer

    Detta är en avhandling från Lund University

    Författare :David Ulmert; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate Cancer Screening; PSA; Prostate Cancer; Klinisk kemi; Clinical chemistry; Early Detection; hK2;

    Sammanfattning : Concentrations of prostate-specific antigen (PSA) and human kallikrein 2 (hK2) were investigated in blood samples that had been obtained from men who were diagnosed with prostate cancer (PCa) decades later. The studies were based on a cohort comprising 22,444 men who, in 1974?1986, were early middle aged and represented a non-PCa-screened population. LÄS MER

  2. 2. The Kallikrein-Related Peptidases hK2 and PSA with Emphasis on Genetic Variation, Secretion, and Sperm Motility

    Detta är en avhandling från Lund University

    Författare :Charlotta Sävblom; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human glandular kallikrein 2; KLK3; hk2; prostate-specific antigen; PSA; sperm motility; seminal plasma; androgen receptor; SNP; CAG; KLK2;

    Sammanfattning : Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are secreted by the prostate into seminal plasma and through leakage into blood. This leakage increases rapidly in prostate disease, and PSA is used worldwide as a marker of prostate cancer. LÄS MER

  3. 3. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Charlotte Becker; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; screening; prostate cancer; PSA; Human glandular kallikrein; hK2; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. LÄS MER

  4. 4. Metabolism of free and complexed prostate - specific antigen and their utility for diagnosis and prognosis of prostate cancer

    Detta är en avhandling från Department of Urology, Malmö University Hospital, 205 02 Malmö, Sweden

    Författare :Thomas Björk; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benign prostatic hyperplasia; alpha-1-antichymotrypsin; PSA; prostate cancer; prostate-specific antigen; Urology; nephrology; Urologi; nefrologi;

    Sammanfattning : Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). LÄS MER

  5. 5. Impact of renal dysfunction on serum Prostate-Specific Antigen

    Detta är en avhandling från Department of Nephrology and Transplantation, Lund University

    Författare :Laila Bruun; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urologi; hK2; Urology; intra-individual variation; elimination; peritoneal dialysis; renal dysfunction; kidney transplantation; hemodialysis; nefrologi; nephrology; PSA;

    Sammanfattning : Measurement of prostate-specific antigen (PSA) in blood is an important tool in detection for prostate cancer. PSA occurs in several molecular forms in blood: mainly as a free form with a molecular mass of 28 kDa; and as PSA complexed to alpha-1-antichymotrypsin, complexed PSA, with a molecular mass of 90 kDa. LÄS MER