Sökning: "sex-steroid hormones"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden sex-steroid hormones.

  1. 1. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

    Författare :Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). LÄS MER

  3. 2. Sex steroid effects on normal breast tissue

    Författare :Gunnar Söderqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Estrogen receptor; progesterone receptor; proliferation; breast epithelialcells; mammary epithelium; sulfatase; 17 HSD; regional differences; sex steroids;

    Sammanfattning : In Sweden, it is estimated that about one million women are treated with estrogen/progestogen for contraception and hormone replacement therapy (HRT). The possibility of an increased cancer risk in target organs has been vividly discussed for many years. LÄS MER

  4. 3. Register-based studies of sex steroid hormones and psychiatric disorders

    Författare :Vide Gotby; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The focus of this thesis is the interplay between sex steroid hormones, psychiatric- and neurodevelopmental disorders and adverse behavioral outcomes. Sex steroid hormones are mostly known for their role in sexual differentiation and reproduction, but have been suggested to be involved the etiology of several psychiatric disorders and in adverse behaviors that show prominent sex differences in prevalence. LÄS MER

  5. 4. Sex steroid hormone receptors : inner ear and hearing

    Författare :Rusana Simonoska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It is well known that hearing loss is more profound in elderly males than females, regardless of noise exposure. Also, an age-related hearing decline starts much earlier in males, already after the age of 30, while in women, the decline does not start until the age of 50. LÄS MER

  7. 5. Prognostic factors for squamous cell cervical cancer : tumor markers, hormones, smoking, and S-phase fraction

    Författare :Annika Lindström; Dan Hellberg; Roger Henriksson; Ulf Stendahl; Sonia Andersson; Umeå universitet; []
    Nyckelord :Cervical cancer; squamous cell carcinoma; sex steroid hormones; smoking; S-phase fraction; tumor markers; LRIG1; prognosis.; MEDICINE; MEDICIN; Oncology; onkologi;

    Sammanfattning : Cervical cancer is the second most common malignancy in women worldwide and one of the leading causes of cancer mortality globally. In patients with invasive cervical cancer prognostic factors are of value for the choice of treatment, monitoring of treatment and follow-up. LÄS MER