Sökning: "NATURVETENSKAP Kemi Organisk kemi"

Visar resultat 31 - 35 av 884 avhandlingar innehållade orden NATURVETENSKAP Kemi Organisk kemi.

  1. 31. Green Chemistry in Chemical Education and Synthetic Applications of Sulfinamides

    Författare :Björn Blomkvist; Peter Dinér; José Alemán; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sulfinamide; Green Chemistry; Chiral Auxiliary; Photoredox; Teaching; Sulfinamid; Grön Kemi; Kiral Hjälpgrupp; Fotoredox; Undervisning; Kemi; Chemistry;

    Sammanfattning : The preparation of chiral molecules, i.e. compounds that are not identical to their mirror image, is of great interest in the field of organic chemistry. LÄS MER

  3. 32. Discovery-Oriented Screening of Dynamic Systems: Combinatorial and Synthetic Applications

    Författare :Marcus Angelin; Olof Ramström; Stefan Kubik; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chemical education; crystallization; dynamic combinatorial chemistry; dynamic combinatorial resolution; dynamic system; enzyme catalysis; isoindolinone; lipase; nitroalcohol; nitroaldol reaction; phthalide; reversible; secondary alcohol; systems chemistry; tandem reaction; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi;

    Sammanfattning : This thesis is divided into six parts, all centered around the development of dynamic (i.e., reversibly interacting) systems of molecules and their applications in dynamic combinatorial chemistry (DCC) and organic synthesis. LÄS MER

  4. 33. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence

    Författare :Erik Chorell; Fredrik Almqvist; Stephen Hanessian; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pilicide; curlicide; anti-virulence; chaperone usher pathway; antibacterial; pili; curli; Escherichia coli; biofilm inhibitor; 2-pyridone; peptidomimetic; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi; Pharmaceutical chemistry; Läkemedelskemi; Organic synthesis; Organisk syntes; Infectious diseases; Infektionssjukdomar; Biorganic Chemistry; bioorganisk kemi; Infectious Diseases; infektionssjukdomar; datorlingvistik; computational linguistics; organisk kemi; Organic Chemistry;

    Sammanfattning : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. LÄS MER

  5. 34. Development of Aerobic Oxidative N-Heterocyclic Carbene Catalysis via Multistep Electron Transfer and its Application

    Författare :Anton Axelsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dihydropyranone; Michael addition; kinetics.; aerobic oxidation; acylation; N-heterocyclic carbene; green chemistry; Organocatalysis; electron transfer mediator; asymmetric synthesis;

    Sammanfattning : Oxidation reactions are ubiquitous in synthetic chemistry, but generally suffer from formation of large amounts of potentially toxic byproducts. Aerial oxygen represents an ideal oxidant since it is inexpensive, non-toxic and only forms water as a byproduct. LÄS MER

  7. 35. Exploring molecular interactions between polypeptide conjugates and protein targets : Manipulating affinity by chemical modifications

    Författare :Aleksandra Balliu; Lars Baltzer; Oliver Seitz; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; polypeptide conjugates; protein targets; molecular recognition; affinity enhancement; conjugation;

    Sammanfattning : In this thesis molecular interactions between polypeptide conjugates and protein targets were investigated. Polypeptides were derivatized with small organic molecules, peptides and oligonucleotides. New strategies were developed with the aim to increase affinities for proteins of biological interest. LÄS MER