Hittade 3 avhandlingar innehållade ordet anti-virulence.
1. Towards Anti-Virulence Antimicrobials, Discovery and Development of Sortase A Inhibitors and Investigations of Bacterial Phenotypes
Sammanfattning : Antibiotic resistance is an emerging and serious threat to public health. Immediate actions are required to preserve current antibiotics while intensifying research efforts towards the development of new effective therapeutics. LÄS MER
2. New alternatives to combat Listeria monocytogenes and Chlamydia trachomatis Design, synthesis, and evaluation of substituted ring-fused 2-pyridones as anti-virulent agentsDetta är en avhandling från Umeå : Umeå universitet
Sammanfattning : Antibiotic resistance has become a global health burden with the number of resistant bacteria continuously increasing. Antibiotic drugs act by being either bactericidal (killing bacteria) or bacteriostatic (inhibiting growth of bacteria). However, these modes of action increase the selective pressure on the bacteria. LÄS MER
3. Pilicides and Curlicides Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulenceDetta är en avhandling från Umeå : Umeå universitet, Kemiska Institutionen
Sammanfattning : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. LÄS MER