Sökning: "Mikael Nilsson"

Visar resultat 1 - 5 av 45 avhandlingar innehållade orden Mikael Nilsson.

  1. 1. Protein–DNA Recognition : In Vitro Evolution and Characterization of DNA-Binding Proteins

    Författare :Mikael Nilsson; Mikael Widersten; Dan Tawfik; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; In vitro evolution; Phage display; mRNA display; Cro; DNA recognition; repressor; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : DNA-recognizing proteins are involved in a multitude of important life-processes. Therefore, it is of great interest to understand the underlying mechanisms that set the rules for sequence specific protein–DNA interactions. Previous attempts aiming to resolve these interactions have been focused on naturally occurring systems. LÄS MER

  2. 2. Biochemical and epidemiological characterization of serogroup C rotavirus

    Författare :Mikael Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rotaviruses are classified into seven serogroups (A-G) on the basis of antigenic and genetic properties. Group A rotavirus is the most common cause of diarrhea in infants and young children in both developing and developed countries. LÄS MER

  3. 3. Insulinogenic Effects of Milk- and Other Dietary Proteins, Mechanisms and metabolic implications

    Författare :Mikael Nilsson; Institutionen för livsmedelsteknik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Näringslära; Nutrition; Type 2 diabetes; Isolated islets; Incretin hormones; Food proteins; Amino acids; Insulin index; Glycaemic index; Hyperinsulinaemia; Insulin; Blood glucose; Milk; Whey;

    Sammanfattning : The metabolic syndrome (type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, dyslipidaemia, and hyperinsulinaemia), is increasing in prevalence world-wide. The progression of this syndrome proceeds through a step-wise deterioration of metabolic events where deterioration of insulin sensitivity appears to have a key role in a ?vicious circle? of hyperinsulinaemia/hyperglycaemia and insulin resistance. LÄS MER

  4. 4. On Feature Extraction and Classification in Speech and Image Processing

    Författare :Mikael Nilsson; []

    Sammanfattning : The natural world is home to innumerable patterns in various forms, which humans are able to locate and interpret by means of the senses. This thesis presents and explores different techniques that mimic such behavior through the use of artificial sensors and computational power, i.e. LÄS MER

  5. 5. Ribosomes and subunits from Escherichia coli studied by asymmetrical flow field-flow fractionation

    Författare :Mikael Nilsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; VHb; Vitreoscilla hemoglobin; E. coli; Escherichia coli; separation; subunits; ribosomes; Asymmetrical flow field-flow fractionation; flow FFF; optimization; biotechnological production; Analytical chemistry; Analytisk kemi;

    Sammanfattning : In this thesis asymmetrical flow field-flow fractionation (FFF) separations of ribosomes and subunits have been studied. Ribosomal material was prepared from Escherichia coli (E. coli) cells and analyzed by the size separation technique. LÄS MER