Sökning: "repressor"

Visar resultat 1 - 5 av 149 avhandlingar innehållade ordet repressor.

  1. 1. Protein–DNA Recognition : In Vitro Evolution and Characterization of DNA-Binding Proteins

    Författare :Mikael Nilsson; Mikael Widersten; Dan Tawfik; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; In vitro evolution; Phage display; mRNA display; Cro; DNA recognition; repressor; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : DNA-recognizing proteins are involved in a multitude of important life-processes. Therefore, it is of great interest to understand the underlying mechanisms that set the rules for sequence specific protein–DNA interactions. Previous attempts aiming to resolve these interactions have been focused on naturally occurring systems. LÄS MER

  3. 2. Function and regulation of the Yeast Mig1 repressor

    Författare :Jonas Östling; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; glucose repression; Mig1; zinc finger protein; Saccharomyces cerevisiae; Kluyveromyces marxianus; Snf1; Biokemi; Biochemistry; Biokemi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Glucose repression is a global regulatory response in the yeast Saccharomyces cerevisiae. Thus, in the presence of glucose, the preferred carbon source, expression of many genes encoding proteins required for metabolism of other carbon sources are turned off.An important mediator of glucose repression is the Mig1 repressor. LÄS MER

  4. 3. Design, Development and Applications of Highly Sensitive Protein-Based Capacitive Biosensors

    Författare :Ibolya Bontidean; Kemiska institutionen; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biotechnology; Contaminated soil; Heavy metals; Lac repressor; Phytochelatin; MerP; MerR; SmtA; Self-assembled monolayer; Biosensor; Capacitance;

    Sammanfattning : Highly sensitive biosensors were developed for environmental and medical applications. The biosensors were based on bioengineered proteins as biorecognition elements coupled to a highly sensitive capacitive transducer. LÄS MER

  5. 4. Structural and functional studies of biomolecules with NMR and CD spectroscopy

    Författare :Evangelos Papadopoulos; Astrid Gräslund; Göran Karlsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR; protein structure; nouse Doppel; HTH; C-repressor; potassium channel; Biophysics; Biofysik; Biophysics; biofysik;

    Sammanfattning : Experimentally derived biomolecular structures were determined by Nuclear Magnetic Resonance (NMR). The properties of selected peptides and proteins in solution and in membrane mimicking micelles were observed by circular Dichroism (CD), mass spectrometry (MS), and other spectroscopic techniques. LÄS MER

  7. 5. Dynamic regulation of the Mig1 transcriptional repressor under glucose de/repression

    Författare :Sviatlana Shashkova; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cell signalling; glucose repression; Mig1; phosphorylation; Saccharomyces cerevisiae;

    Sammanfattning : The budding yeast Saccharomyces cerevisiae AMP-activated protein kinase/SNF1 is a member of a highly conserved protein family present in all eukaryotes. Snf1 regulates energy homeostasis; in yeast, it is best-known for its role in cellular adaptation to glucose limitation. LÄS MER