Sökning: "MCA"

Visar resultat 11 - 15 av 47 avhandlingar innehållade ordet MCA.

  1. 11. Expression of TGF- isoforms, their receptors and related SMAD proteins in brain pathology : Immunohistochemical studies focusing on infarcts, abscesses and malignant gliomas

    Författare :Ahmad Khaled Ata; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; TGF-beta receptor; SMAD; brain; infarct; abscess; glioma; experimental; human; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik;

    Sammanfattning : This thesis focuses on the immunohistochemical expression of transforming growth factor beta(TGFβ) isoforms, their receptors and TGF-β-related SMAD proteins in brain pathology, chiefly in-farcts. One key question was whether the expressions of these compounds are altered within glial cells, endothelial cells of microvessels and other cell types in the vicinity of infarcts. LÄS MER

  3. 12. The cerebral circulation in preeclampsia : abnormalities in autoregulation and perfusion

    Författare :Michael A Belfort; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :preeclampsia; eclampsia; autoregulation; cerebral perfusion pressure; Doppler; central retinal artery; ophthalmic artery; middle cerebral artery; magnesium sulfate; nimodipine; headache; scotomata;

    Sammanfattning : Background: Eclampsia continues to be a major cause of maternal death. Abnormal cerebral blood flow and autoregulation may play an important role in the causation. Doppler ultrasound now allows assessment of the pathophysiology of preeclampsia, and the mechanisms of action of drugs used to treat it. LÄS MER

  4. 13. Vascular receptor changes in ischemic stroke

    Författare :Emelie Stenman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

    Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER

  5. 14. Importance of MAPK and PKC in cerebrovascular endothelin receptor changes

    Författare :Marie Henriksson; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; farmakognosi; farmaci; toxikologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; Kardiovaskulära systemet; Cardiovascular system; Fysiologi; Physiology; cerebral arteries; ischemia; receptors; endothelin; Farmakologi;

    Sammanfattning : Endothelin is a vasoactive peptide that exerts its effect through two receptors; the endothelin type A (ETA) and type B (ETB) receptor. The contractile ETA receptor is localized on smooth muscle cells in the vascular wall, while the ETB receptors are mainly situated on endothelial cells, mediating vasodilatation. LÄS MER

  7. 15. Summer Climate Variability during the Past 1200 Years in Central Scandinavia – A Tree-Ring Perspective

    Författare :Peng Zhang; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Central Scandinavia; climate variability; dendroclimatology; maximum latewood density; Medieval Climate Anomaly; model-proxy data comparison; Pinus sylvestris L.; temperature; tree-ring width;

    Sammanfattning : To set the current 20th century warming in a long-term context, significant efforts have been made to reconstruct hemispheric-to-global temperatures beyond the instrumental period. Tree-rings, which have annual resolution and can be precisely dated, have been widely used to infer past climate variability. LÄS MER