Sökning: "thrombotic thrombocytopenic purpura"
Hittade 4 avhandlingar innehållade orden thrombotic thrombocytopenic purpura.
1. Studies of the pathogenesis of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura
Sammanfattning : This study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. LÄS MER
2. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura
Sammanfattning : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. LÄS MER
3. Studies of ADAMTS13 expression and activity in the kidney
Sammanfattning : Von Willebrand factor (VWF) is an abundant plasma glycoprotein involved in platelet adhesion and aggregation at sites of vascular injury. ADAMTS13 is the sole physiological VWF-cleaving protease, thus regulating the size of thrombus growth. LÄS MER
4. Verotoxinogenic Escherichia coli O157:H7 in Swedish cattle and pigs
Sammanfattning : Verotoxinogenic E. coli O157:H7 (VTEC O157:H7) can cause severe disease in humans, with bloody diarrhea and complications such as haemolytic uraemic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP) and even death. Animals carry VTEC O157:H7 asymptomatically. LÄS MER