Sökning: "Helena Lindgren"

Visar resultat 6 - 10 av 20 avhandlingar innehållade orden Helena Lindgren.

1. 6. The Histidine-rich Glycoprotein in Reproduction

   Författare :Karin E Lindgren; Inger Sundström-Poromaa; Helena Åkerud; Eva Wiberg-Itzel; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; embryo culture medium; embryogenesis; embryonic secretome; endometrium; histidine-rich glycoprotein; human embryo development; human embryo implantation; human endometrial endothelial cells; in vitro fertilisation; infertility; male infertility; proximity extension assay; recurrent miscarriage; single nucleotide polymorphism; sperm quality; time-lapse technique; vascular endothelial growth factor;

   Sammanfattning : Infertility affects 15% of reproductive-aged couples. The milieu surrounding the growing embryo is of outmost importance, and should be optimised during in vitro fertilisation (IVF). Many biological processes, such as angiogenesis, coagulation, and immune processes need to be well regulated for a pregnancy to occur and progress normally. LÄS MER

3. 7. Exploring Inhibitors of HIV-1 Protease : Interaction Studies with Applications for Drug Discovery

   Författare :Maria T. Lindgren; Helena Danielson; Jozsef Tözser; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; kinetics; biosensors; ADME; drug discovery; SPR; resistance; inhibition; copper; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : A variety of HIV-1 protease inhibitors and their interactions with the enzyme have been characterized in order to identify novel and improved drugs against AIDS. The investigated inhibitors were represented by clinical and non-clinical inhibitors, active site and allosteric inhibitors, transition-state analogues and metal-ions. LÄS MER

4. 8. Awareness of fetal movements and pregnancy outcomes

   Författare :Anna Akselsson; Ingela Rådestad; Helena Lindgren; Susanne Georgsson; Anna Dencker; Karolinska Institutet; Karolinska Institutet; Sophiahemmet Högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Fetal movements are one, among others, of the measurable factors indicating wellbeing of the fetus. Decreased fetal movements are associated with intrauterine growth restriction and stillbirth. Women with experience of stillbirth have often noticed decreased and weaker fetal movements preceding the intrauterine death. LÄS MER

5. 9. Adaptive human-agent dialogues for reasoning about health

   Författare :Jayalakshmi Baskar; Helena Lindgren; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The aim of this research is to develop new theories, methods and technology, which enables adaptive and personalised dialogues between a human and a software agent, to handle everyday queries about health that are perceived as meaningful and useful to the human. Some of the challenges to build such human-agent dialogue system are the following. LÄS MER

7. 10. A Case-Based Reasoning System for the Diagnosis of Individual Sensitivity to Stress in Psychophysiology

   Författare :Shahina Begum; Peter Funk; Helena Lindgren; Mälardalens högskola; []
   Nyckelord :Artificial Intelligence; Case-based reasoning; Sensor; Signals; Stress; Diagnosis; Computer-based system; TECHNOLOGY; TEKNIKVETENSKAP; Datavetenskap; Computer Science;

   Sammanfattning : Increased stress is a continuing problem in our present world. Especiallynegative stress could cause serious health problems if it remainsundiagnosed/misdiagnosed and untreated. In the stress medicine, clinicians’measure blood pressure, ECG, finger temperature and breathing rate during anumber of exercises to diagnose stress-related disorders. LÄS MER