Sökning: "histidine-rich glycoprotein"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden histidine-rich glycoprotein.

  1. 1. The Histidine-rich Glycoprotein in Reproduction

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Karin E Lindgren; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; embryo culture medium; embryogenesis; embryonic secretome; endometrium; histidine-rich glycoprotein; human embryo development; human embryo implantation; human endometrial endothelial cells; in vitro fertilisation; infertility; male infertility; proximity extension assay; recurrent miscarriage; single nucleotide polymorphism; sperm quality; time-lapse technique; vascular endothelial growth factor;

    Sammanfattning : Infertility affects 15% of reproductive-aged couples. The milieu surrounding the growing embryo is of outmost importance, and should be optimised during in vitro fertilisation (IVF). Many biological processes, such as angiogenesis, coagulation, and immune processes need to be well regulated for a pregnancy to occur and progress normally. LÄS MER

  2. 2. ANTIMICROBIAL ACTIVITIES OF HISTIDINE-RICH GLYCOPROTEIN AND CATIONIC PEPTIDES

    Detta är en avhandling från Institutionen för kliniska vetenskaper, Lunds universitet

    Författare :Victoria Rydengård; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatologi; venereologi; venereology; Dermatology; histidine-rich glycoprotein; heparin-binding; zinc; low pH; Medicine human and vertebrates ; Medicin människa och djur ; innate immunity; antimicrobial;

    Sammanfattning : In an environment full of potential pathogens it is of importance for organisms to mount a fast and effective defence. Antimicrobial peptides are ancient and integral effector molecules of the innate immune system. They are found in all kinds of species from bacteria to plants and animals, indicating their importance during evolution. LÄS MER

  3. 3. The Role of Histidine-rich Glycoprotein in Angiogenesis and Tumor Growth

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Åsa Thulin; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histidine-rich glycoprotein; HRG HRGP HPRG; angiogenesis inhibitor; cancer; VEGF; platelets; MEDICINE; MEDICIN; Medicin; Medicine;

    Sammanfattning : Histidine-rich glycoprotein (HRG) is a heparin-binding plasma protein modulating immune, hemostatic and vascular functions. I have studied the antiangiogenic functions of HRG in vitro and in vivo in order to understand the molecular mechanisms of action of HRG as an angiogenesis inhibitor. LÄS MER

  4. 4. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Chunsik Lee; Uppsala universitet.; [2006]
    Nyckelord :Cell and molecular biology; anti-angiogenesis; angiogenesis inhibitor; endothelial cell; histidine-rich glycoprotein; focal adhesion; tumor-associated macrophages; VEGF; MMP; Cell- och molekylärbiologi;

    Sammanfattning : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. LÄS MER

  5. 5. Cellular Origin and Development of Glioma

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nanna Lindberg; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; brain tumor; PDGF; RCAS TV-A; cell of origin; glial cell; oligodendrocyte progenitor cell; DNA repair; homology-directed repair; RAD51; angiogenesis; histidine-rich glycoprotein; MEDICINE Morphology; cell biology; pathology; MEDICIN Morfologi; cellbiologi; patologi; Molecular Medicine; molekylär medicin genetik och patologi ;

    Sammanfattning : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. LÄS MER