Sökning: "Helena Åkerud"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Helena Åkerud.

1. 1. The Effects of SSRI Treatment on Human Placenta and Embryo

   Författare :Helena Kaihola; Helena Åkerud; Inger Sundström-Poromaa; Jocelien Olivier; Olav Spigset; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antenatal depression; embryo; embryo development; fluoxetine; gene expression; NGF; placenta; protein expression; Raf-1; ROCK; signaling pathways; SSRI; Medicinsk vetenskap; Medical Science; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : During pregnancy, 4 - 7% of women suffer from major depressive disorder. When antidepressive treatment is needed, selective serotonin reuptake inhibitors (SSRIs) are the most commonly used. Although severe complications from SSRI treatment are rare, association with a number of adverse pregnancy and fetal outcomes has been found. LÄS MER

3. 2. Cerebral biomarkers in women with preeclampsia

   Författare :Lina Bergman; Helena Åkerud; Anna Karin Wikström; Johan Wikström; Eva Britta Råssjö; Ulf Högberg; Marc Spandermaan; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preeclampsia; eclampsia; biomarkers; S100B; NSE; PRES; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Preeclampsia and eclampsia are among the most common causes of maternal and fetal mortality and morbidity worldwide. There are no reliable means to predict eclampsia or cerebral edema in women with preeclampsia and knowledge of the brain involvement in preeclampsia is still limited. LÄS MER

4. 3. Pre-eclampsia – Possible to Predict? : A Biochemical and Epidemiological Study of Pre-eclampsia

   Författare :Marie Bolin; Helena Åkerud; Anna-Karin Wikström; Inger Sundström-Poromaa; Karel Marsal; Uppsala universitet; []
   Nyckelord :pre-eclampsia; angiopoietin; histidine-rich glycoprotein; hyperemesis gravidarum; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Pre-eclampsia is a major cause of maternal and perinatal morbidity and mortality worldwide. A predictor of pre-eclampsia would enable intervention, close surveillance and timely delivery, and thereby reduce the negative consequences of the disorder. LÄS MER

5. 4. Genetics and Labor Pain Behavior

   Författare :Fatimah Dabo Pettersson; Helena Åkerud; Inger Sundström Poromaa; Fred Nyberg; Pelle Lindqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anxiety; beta-endorphin; depressed mood; GCH1; labor analgesia; labor pain; OPRM1; SNP; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Labor may perhaps be the most painful a woman might experience, although characterized by large inter-individual variability. The perceived pain during labor is the result of diverse factors, i.e. her previous pain experiences, the analgesia she receives and maybe also her genes. LÄS MER

7. 5. Biological Aspects of Peripartum Depression

   Författare :Åsa Edvinsson; Inger Sundström Poromaa; Helena Åkerud; Jocelien Olivier; Charlotte Hellgren; Isis Amer-Wåhlin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peripartum depression; antenatal depression; postpartum depression; antidepressant treatment; selective serotonin reuptake inhibitor; SSRI; pregnancy; postpartum; attentional bias; Emotional Stroop Task; inflammatory markers; proximity extension assay; placenta; gene expression; TaqMan low-density array; protein expression; immunohistochemistry; HTR1A; NPY2R;

   Sammanfattning : Peripartum depression affects around 12% of women in pregnancy and postpartum, and about 2–3% of European pregnant women use antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs). An increased risk of poor pregnancy outcomes has been described in women with antenatal depression and SSRI treatment during pregnancy. LÄS MER