Sökning: "thyroid function"

Visar resultat 16 - 20 av 83 avhandlingar innehållade orden thyroid function.

  1. 16. Long-term radiobiological effects of 131I exposure - dose, age and time related transcriptomatic and proteomic rasponse in rats

    Författare :Malin Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiation; thyroid; plasma; late effects; biomarkers; transcript; protein;

    Sammanfattning : 131I is commonly used in the clinic for treating thyroid diseases, using the physiological uptake of iodine in thyroid, but also for other target tissues. 131I is also commonly released during nuclear accidents. LÄS MER

  3. 17. Growth factor receptor signalling in thyrocytes of normal and neoplastic origin

    Författare :Daniel Bergström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; thyroid; carcinoma; HGF; Met; TGF-β; EGF; receptor signalling; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Cellular growth and function are controlled by stimulatory and inhibitory factors actingthrough specific receptors. The present thesis focuses on the role of growth factors, theirreceptors and signalling pathways in normal and neoplastic thyroid epithelial cell biology. LÄS MER

  4. 18. Genetic and Genomic Studies in Chicken : Assigning Function to Vertebrate Genes

    Författare :Jonas Eriksson; Leif Andersson; Greger Larson; Göran Hjälm; Tosso Leeb; Uppsala universitet; []
    Nyckelord :Chicken; BCO2; TSHR; COMTD1; Phenotypic variation; Domestication; Selective sweeps; Pigmentation; Molekylär genetik; Molecular Genetics;

    Sammanfattning : A major challenge in the post-genomic era is to understand how genome sequence variants (genotype) give rise to the enormous diversity observed in terms of morphology, physiology and behavior (phenotype) among living organisms. Domestic animals—with their tremendous phenotypic variation—are excellent model organisms for determining the relationships between genotype and phenotype. LÄS MER

  5. 19. Down syndrome : Growth and endocrine impact

    Författare :Åsa Myrelid; Jan Gustafsson; Göran Annerén; Ann-Christine Lindgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Down syndrome; growth; growth charts; body proportions; growth hormone; thyroid function; metabolism; body composition; cognition; motor development; Downs syndrom; tillväxt; tillväxtkurvor; kroppsproportioner; tillväxthormon; sköldkörtelfunktion; metabolism; kroppssammansättning; kognitiv förmåga; motorisk utveckling; Paediatric medicine; Pediatrisk medicin; pediatrik; Pediatrics;

    Sammanfattning : Down syndrome (DS) is associated with psychomotor retardation, short stature and endocrine dysfunction. Statural growth is a well-known indicator of health. The growth in DS differs markedly from that of other children and there is a 20 cm reduction of final height as compared to target height. LÄS MER

  7. 20. Interactions between the stroma and thyroid epithelial cells of normal and malignant origin

    Författare :Thérèse Dahlman; Uppsala universitet; []
    Nyckelord :Medical sciences; Thyroid gland; carcinoma; collagen type I; EGF; TGF-b1; interaction; integrins; E-cadherin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Endocrine and locally produced factors as well as interactions between epithelial cells and the stroma important in the control of growth and function of the thyroid gland. In this study, the effects of, and mechanism(s) for, such cross-talk under some normal and pathological conditions were investigated. LÄS MER