Sökning: "systemic design"
Visar resultat 11 - 15 av 126 avhandlingar innehållade orden systemic design.
11. Towards Systemic Governance of Critical Infrastructure Protection : State and Relevance of a Swedish Case
Sammanfattning : The protection of infrastructure that is critical to society’s functionality, survival and progression has gained significance for both national security and research because of its large-scale and interdependent nature. Critical infrastructure can be viewed as a complex, socio-technical system-of-systems that imposes extensive requirements on governance efforts to foster critical infrastructure protection (CIP), regardless of whether it involves public organisations, private organisations or both. LÄS MER
12. Product-Service System Designing for Environmental Sustainability : Insights into Design Cognition of Experienced Product Developers
Sammanfattning : The overall objective of this research is to support practitioners within the manufacturing industry to effectively design product-service system (PSS)-based solutions with relatively lower environmental impacts than typical product-centric solutions. Design research methodology (DRM) is applied to systematically address this objective with both descriptive and prescriptive approaches. LÄS MER
13. Life Cycle Energy Optimisation: A multidisciplinary engineering design optimisation framework for sustainable vehicle development
Sammanfattning : This thesis explores how the systemic-level environmental footprint of light-duty vehicles could be reduced through integrative design using the Life Cycle Energy Optimisation (LCEO) methodology. This methodology aims at finding a design solution that uses a minimum amount of cumulative energy demand over the different phases of the vehicle's life cycle; while complying with a set of functional constraints, thereby avoiding any sub-optimal energy demand shifts between the vehicle's different life cycle phases. LÄS MER
14. Approaches to soft drug analogues of dihydrofolate reductase inhibitors : Design and synthesis
Sammanfattning : The main objective of the research described in this thesis has been the design and synthesis of inhibitors of the enzyme dihydrofolate reductase (DHFR) intended for local administration and devoid of systemic side-effects. The blocking of the enzymatic activity of DHFR is a key element in the treatment of many diseases, including cancer, bacterial and protozoal infections, and also opportunistic infections associated with AIDS (Pneumocystis carinii pneumonia, PCP). LÄS MER
15. User experiences with flexible offices
Sammanfattning : Different office types provide the preconditions for distinct user experiences. However, research evidence on how users appraise flexible offices such as activity-based or combi offices is not as abundant as in the case of the more traditional open-plan and cell offices. LÄS MER
