Sökning: "stress chain"

Visar resultat 21 - 25 av 119 avhandlingar innehållade orden stress chain.

  1. 21. Mitochondrial translation and its impact on protein homeostasis and aging

    Författare :Tamara Suhm; Martin Ott; Aleksandra Trifunovic; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondrial ribosome; mitochondrial translation accuracy; mitochondrial communication; interorganellar communication; stress signaling; proteostasis; aging; yeast genetics; mitochondrial protein quality control; mitochondrial membrane protein insertion; Biochemistry; biokemi;

    Sammanfattning : Besides their famous role as powerhouse of the cell, mitochondria are also involved in many signaling processes and metabolism. Therefore, it is unsurprising that mitochondria are no isolated organelles but are in constant crosstalk with other parts of the cell. LÄS MER

  3. 22. Dietary Fatty Acids and Inflammation : Observational and Interventional Studies

    Författare :Helena Bjermo; Ulf Risérus; Tommy Cederholm; Parveen Yaqoob; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dietary fat; Fatty acids; Serum fatty acid composition; Linoleic acid; Stearoyl coenzymeA desaturase; SCD-1; Inflammation; C-reactive protein; Oxidative stress; Lipid peroxidation; Isoprostanes; Prostaglandins; Obesity; Epidemiology; Dietary intervention; Metabolic syndrome; Nutrition; Näringslära; Epidemiology; Epidemiologi; Public health science; Folkhälsovetenskap; Immunology; Immunologi; Diabetology; Diabetologi; Cardiology; Kardiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Dietary fat quality influences the risk of type 2 diabetes and cardiovascular disease. A low-grade inflammation is suggested to contribute to the disease development, often accompanied by obesity. Whereas n-3 polyunsaturated fatty acids (PUFA) have been considered anti-inflammatory, n-6 PUFA have been proposed to act pro-inflammatory. LÄS MER

  4. 23. Modelling Aspects in Forming and Welding of Nickel-Base Superalloys

    Författare :Lluís Pérez Caro; Mats Oldenburg; Eva-Lis Odenberger; Juan Carlos Cante Teran; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; alloy 718; Haynes 282; cold forming; hot forming; material characterization; GISSMO; welding; heat treatment; manufacturing chain; springback; shape distortions; dynamic strain aging; DSA; microstructure; Hållfasthetslära; Solid Mechanics;

    Sammanfattning : The reduction of fuel consumption and carbon dioxide emissions are currently a key factor for the aviation industry because of major concerns about climate change and more restrictive environmental laws. One way to reduce both fuel consumption and CO2 emissions is by significantly decreasing the weight of vehicles while increasing the efficiency of the engine. LÄS MER

  5. 24. Changed iron metabolism and iron toxicity in scrapie-infected neuroblastoma cells

    Författare :Sandra Zetterström Fernaeus; Tiit Land; Gaetano Cairo; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prion disease; oxidative stress; iron metabolism; Neurochemistry; Neurokemi;

    Sammanfattning : Reactions and interactions of iron and oxygen can be both beneficial and detrimental to cells and tissues. Iron is mainly found in our blood where it functions as a mediator in the transport of oxygen to the cells and is further vital for the cellular respiration reducing the oxygen to water. LÄS MER

  7. 25. Oxidative stress and mitochondrial function : role of ubiquinol as antioxidant

    Författare :Patrik Andrée; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Over the last three decades it has been established that biquinone (coenzyme Q), in addition to its function as an electron and proton carrier in the respiratory chain, acts in its reduced form (ubiquinol) as an antioxidant. The main theme of this thesis is a study of the antioxidant function of ubiquinol in preparations of beef heart submitochondrial particles, which consist of inverted vesicular fragments of the inner mitochondrial membrane. LÄS MER