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1. 1. Immunomodulatory properties of steroid hormones

   Författare :Maria Taube; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DTH; oestradiol; corticosteroids; T cells; SCID mice; adoptive transfer; thymus; spleen.;

   Sammanfattning : Recent epidemiological, clinical and experimental evidence have suggested that steroid hormones play an important role in immune responses and in immune-mediated diseases. Many autoimmune diseases are treated with corticosteroids. LÄS MER

3. 2. Equine glutathione transferase A3-3 : an efficient steroid isomerase

   Författare :Helena Lindström; Bengt Mannervik; Ann-Kristin Östlund Farrants; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Equine; glutatione transferase; steroidogenesis; steroid isomerase; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication by making toxic electrophiles more polar and therefore more easily excretable. However some GSTs have developed alternative functions. LÄS MER

4. 3. Human vaginal epithelial immunity and influences of hormonal contraceptive usage

   Författare :Anna Ildgruben; Nils Lycke; Umeå universitet; []
   Nyckelord :human vaginal epithelium; hormonal contraceptives; epithelial thickness; intraepithelial immune cells; steroid receptors; steroid hormones; defensins; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : The vagina is the port of entry for sexually transmitted diseases in women. Its epithelium constitutes the luminal border, thus comprising an important defence barrier. LÄS MER

5. 4. Ovarian Steroid Hormones, Emotion Processing and Mood

   Författare :Malin Gingnell; Inger Sundström-Poromaa; Mats Fredrikson; Johan Wikström; Larry Cahill; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; premenstrual dysphoric disorder; menstrual cycle; combined oral contraceptives; estrogen; estradiol; progesterone; ethinyl-estradiol; levonorgestrel; randomized clinical trial; placebo; fMRI; amygdala; ACC; insula; dlPFC; mPFC; IFG; MFG; Medicinsk vetenskap; Medical Science; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : It is known that some psychiatric disorders may deteriorate in relation to the menstrual cycle. However, in some conditions, such as premenstrual dysphoric disorder (PMDD), symptomatology is triggered mainly by the variations in ovarian steroid hormones. LÄS MER

7. 5. Behavioral effects of female sex steroid hormones : models of PMS and PMDD in Wistar rats

   Författare :Magnus Löfgren; Torbjörn Bäckström; Inga-Maj Johansson; Per Södersten; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; Biological research on drug dependence; Biologisk beroendeforskning; Endocrinology; Endokrinologi; Obstetrics and gynaecology; Obstetrik och gynekologi; Pharmacological research; Farmakologisk forskning; Obstetrics and gynaecology; Obstetrik och gynekologi; Psychology; Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). LÄS MER