Sökning: "progesterone"

Visar resultat 1 - 5 av 184 avhandlingar innehållade ordet progesterone.

  1. 1. Progesterone metabolites : learning, tolerance, antagonism & metabolism

    Författare :Charlotte Öfverman; Inga-Maj Johansson; Torbjörn Bäckström; Esa Korpi; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allopregnanolone; isoallopregnanolone; THDOC; learning; tolerance; antagonism; inhibition; patch clamp; Morris water maze; metabolism; epimerization; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Progesterone metabolites as allopregnanolone, isoallopregnanolone and tetrahydrodeoxy-corticosterone (THDOC) are increased in the luteal phase of the menstrual cycle, throughout pregnancy and during stress. Allopregnanolone and THDOC are neurosteroids with 3α-hydroxy, 5α-configurations and positive modulating effect on the GABAA receptor. LÄS MER

  2. 2. The role of progesterone in the regulation of ciliary activity in the fallopian tube

    Författare :Magdalena Nutu; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :progesterone; progesterone receptor; non-genomic progesterone receptor; ciliated cells; fallopian tube; gamete transport; ciliary activity; ciliary beat frequency; reproduction; fertility;

    Sammanfattning : The overall aim of this thesis was to investigate the distribution and regulation of membrane progesterone receptors (mPRs) that may be involved in regulating ciliary activity in the fallopian tube. The fallopian tube serves to transport the egg and spermatozoa to achieve fertilization. LÄS MER

  3. 3. Progesterone in human parturition : progesterone and 5α-pregnane-3,20-dione in relation to human myometrial activity

    Författare :Mats Löfgren; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : This study was undertaken to evaluate the relationship of progesterone and 5α-pregnane-3,20-dione (5αDHP), a major progesterone metabolite, to human parturition. The serum concentrations of 5αDHP prior to, during and following parturition were to be established, as well as its maternal and fetal concentration in different modes of delivery. LÄS MER

  4. 4. Allopregnanolone and mood : studies of postmenopausal women during treatment with progesterone

    Författare :Lotta Andréen; Torbjörn Bäckström; Viveca Odlind; Umeå universitet; []
    Nyckelord :Obstetrics and gynaecology; Progesterone; Allopregnanolone; GABA; mood; bimodal; Obstetrik och kvinnosjukdomar;

    Sammanfattning : Introduction. Allopregnanolone and pregnanolone (neuroactive metabolites of progesterone) act as positive modulators of the GABAA receptor system which is the major inhibitory system in CNS. Contradictory results on the effect of GABAA receptor modulators are reported. LÄS MER

  5. 5. Granulosa cell apoptosis: Transcriptional regulation by the nuclear progesterone receptor

    Författare :P. Anders Friberg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :ovary; granulosa cells; ovulation; luteinization; progesterone; apoptosis; cholesterol synthesis; isoprenylation;

    Sammanfattning : Ovarian follicle atresia caused by granulosa cell apoptosis is a central process in normal female physiology. Progesterone has been reported to be a survival factor in granulosa cells at several developmental stages. LÄS MER