Sökning: "spinal pain"

Visar resultat 11 - 15 av 186 avhandlingar innehållade orden spinal pain.

  1. 11. Biomarkers for Better Understanding of the Pathophysiology and Treatment of Chronic Pain : Investigations of Human Biofluids

    Författare :Anne-Li Lind; Torsten Gordh; Masood Kamali-Moghaddam; Jonas Bergquist; Eva Kosek; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chronic pain; neuropathic pain; lumbar radicular pain; amyotrophic lateral sclerosis; radiculopathy; fibromyalgia; pathophysiology; spinal cord stimulation; mechanism of action; disc herniation; cerebrospinal fluid; plasma; biomarker; human; protein; chemokines; cytokines; inflammation; neuroinflammation; mass spectrometry; proximity ligation assay; proximity extension assay; antibody suspension bead array; protein profiling; molecular medicine; personalized medicine; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Chronic pain affects 20 % of the global population, causes suffering, is difficult to treat, and constitutes a large economic burden for society. So far, the characterization of molecular mechanisms of chronic pain-like behaviors in animal models has not translated into effective treatments. LÄS MER

  3. 12. Temporomandibular disorders : incidence, course, and risk factors

    Författare :Susanna Marklund; Anders Wänman; Gunnar E Carlsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bruxism; dental occlusion; gender; headaches; longitudinal; myofascial pain; orofacial pain; prospective cohort; risk factors; spinal pain; temporomandibular joint; ODONTOLOGY; ODONTOLOGI;

    Sammanfattning : Temporomandibular disorders (TMD) embrace pain and dysfunction in the temporomandibular joint (TMJ) and jaw muscles. TMD is a prevalent condition in the population and constitutes a significant health problem. LÄS MER

  4. 13. Towards a Translational Pain Model - Techniques and developments

    Författare :Leila Etemadi; Neuronano Research Center (NRC); []
    Nyckelord :UVB irradiation; Pain; Neuropeptides; Inflammation; Contralateral; Lateral spinal nucleus; Micro-array electrodes; Pan-neuronal markers; immunohistochemistry;

    Sammanfattning : Pain is a major health issue for each affected individual and has a large impact on health costs. Most of our knowledge about this defensive system rely on data from different animal experiments. There is an obvious need for a translational pain model allowing comparisons between experimental animals and humans. LÄS MER

  5. 14. Plasticity in mice nociceptive spinal circuits -role of cell adhesion molecules

    Författare :Jonas Thelin; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long term-potentiation; Cell adhesion molecule; Pain; Somatosensory imprinting; Medicin människa och djur ; Medicine human and vertebrates ; Nociceptive withdrawal reflex; Species differences; Central sensitisation; Mouse strains; Spinal cord;

    Sammanfattning : Introduction: To understand the function of the genes and their products in the pain system, studies will have to deal with complex issues related to intercellular communication, e.g. plasticity in neuronal networks. LÄS MER

  7. 15. Molecular mechanisms of synaptic transmission and plasticity in spinal sensory pathways

    Författare :Max Larsson; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; neuropsychology; Neurology; electron microscopy; synaptic plasticity; synapse; pain; spinal cord; hyperalgesia; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : An intense, potentially tissue-damaging (noxious) stimulus may lead to enhanced pain sensation of subsequent noxious stimuli (hyperalgesia) and to the perceiving of innocuous stimuli as painful (allodynia). This is thought to result to a large extent from strengthening of synapses established by primary afferent fibers onto spinal cord dorsal horn neurons. LÄS MER