Sökning: "sensory nerve"
Visar resultat 1 - 5 av 192 avhandlingar innehållade orden sensory nerve.
1. The sensational hand. Clinical assessment after nerve repair
Sammanfattning : Following the transection and repair of major nerve trunks in the forearm, the functional outcome is influenced by mechanisms in the peripheral, as well as in the central nervous system. In the present thesis the interest is focused on assessment of the outcome after nerve repair, central nervous factors influencing the outcome, and sense substitution to compensate for sensory loss. LÄS MER
2. Sensory neuronal protection & improving regeneration after peripheral nerve injury
Sammanfattning : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. LÄS MER
3. PACAP and orphanin FQ/nociceptin -Distribution, importance and regulation in sensory neurons and spinal cord
Sammanfattning : Neuropeptide expression in the nervous system is abundant and plastic, and an altered expression after injury is an example of a functional response, helping the neuron to cope with adverse changes, and involves effects on differentiation, synthesis, repair/regeneration, survival, and modulation of signal transmission. I have investigated the distribution/expression of the neuropeptides, orphanin FQ/nociceptin (OFQ/N) and pituitary adenylate cyclase activating polypeptide (PACAP), under normal conditions, in response to nerve injuries, and also studied sensory responses in mice deficient for the PAC1 receptor (PAC1-/-). LÄS MER
4. Development of biosynthetic conduits for peripheral nerve repair
Sammanfattning : Peripheral nerve injuries are often associated with significant loss of nervous tissue leading to poor restoration of function following repair of injured nerves. Although the injury gap could be bridged by autologous nerve graft, the limited access to donor material and additional morbidity such as loss of sensation and scarring have prompted a search for biosynthetic nerve transplants. LÄS MER
5. Sensory nerve fibres, neuropeptides and cartilage : Experimental studies in the rat
Sammanfattning : During development, maintenance and repair after injury, reciprocal interactions occur between the peripheral nervous system and the target tissues. In the Papers presented in this thesis, different aspects of such netvetarget influences between peripheral nerve fibres and skeletal tissues dtuing development and repair have been investigated in the rat. LÄS MER
