Sökning: "trk"

Visar resultat 1 - 5 av 17 avhandlingar innehållade ordet trk.

  1. 1. PACAP in adult sensory neurons - implications in injury and pain

    Författare :Helen Jongsma Wallin; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripheral nerve injury; PAC1; PACAP; neurotrophin; neuropeptide; inflammatory pain; inflammation; gracile nuclei; DRG; formalin test; neurofysiologi; neuropsykologi; Neurologi; neurophysiology; neuropsychology; Neurology; trk;

    Sammanfattning : The data presented in this thesis deal with the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) in adult sensory neurons. We have used different injury and pain models to determine the involvement of PACAP during such conditions. The role of neurotrophins for PACAP expression was also investigated. LÄS MER

  3. 2. PACAP and orphanin FQ/nociceptin -Distribution, importance and regulation in sensory neurons and spinal cord

    Författare :Lina Pettersson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; neuropsychology; Neurology; trk; spinal cord; sensory neuron; rat; PAC1; PACAP; ORL1; OFQ N; neurotrophin; neuropeptide; nerve transection; nerve compression; inflammatory pain; BDNF; DRG;

    Sammanfattning : Neuropeptide expression in the nervous system is abundant and plastic, and an altered expression after injury is an example of a functional response, helping the neuron to cope with adverse changes, and involves effects on differentiation, synthesis, repair/regeneration, survival, and modulation of signal transmission. I have investigated the distribution/expression of the neuropeptides, orphanin FQ/nociceptin (OFQ/N) and pituitary adenylate cyclase activating polypeptide (PACAP), under normal conditions, in response to nerve injuries, and also studied sensory responses in mice deficient for the PAC1 receptor (PAC1-/-). LÄS MER

  4. 3. Studier av trafikantbeteende i olyckor : [utveckling och prövning av en metodik för haveriundersökningar

    Författare :Anders Englund; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Trafiksäkerhet-- Sverige;

    Sammanfattning : .... LÄS MER

  5. 4. Molecular studies of the neurotrophin Trk kinase receptors in the chicken peripheral nervous system

    Författare :Anders Bäckström; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 5. Changes in sensory systems during aging : an experimental study in the rat

    Författare :Esbjörn Bergman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :aging; behavior; primary sensory neuron; dorsal root ganglion; mystacial pad; sensory nerve ending; axon dystrophy; neuropeptides; B4; RT97; CTB; neurotrophins; trk; p75NTR; GFR[alpha]; RET; protein; mRNA;

    Sammanfattning : Aging is associated with sensorimotor disturbances, including increased proprioceptive thresholds. The present study aimed to clarify the occurrence of structural and biochemical alterations in sensory systems of behaviorally characterized aged rats. LÄS MER