Sökning: "leukaemia inhibitory factor"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden leukaemia inhibitory factor.
1. Sensory neuronal protection & improving regeneration after peripheral nerve injury
Sammanfattning : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. LÄS MER
2. Transcriptional regulation of the neuropeptide galanin : special reference to axotomy
Sammanfattning : Galanin is a neuropeptide which is located in both the central and peripheral nervous system. In peripheral neurones, this peptide is thought to be involved in influencing pain sensation after nerve injury (neuropathic pain) and also in the regeneration of peripheral nerves. LÄS MER
3. The Human Endometrium : Studies on Angiogenesis and Endometriosis
Sammanfattning : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. LÄS MER
4. Development of a protein-free fed-batch process for NS0 cells: studies on regulation of proliferation
Sammanfattning : The overall objective of this study was to investigate how NS0 cell proliferation is regulated in protein-free media. The hypothesis was that during the adaptation to growth factor-free media, animal cell lines start to produce their own autocrine growth factors to support proliferation, and after some time in a culture the effects of these factors are lost which results in cessation of proliferation. LÄS MER
5. Growth hormone, JAKs and STATs : a model cytokine signal transduction system
Sammanfattning : The haematopoietic cytokine family of signalling molecules comprises a variety of polypeptides which have pleiotropic effects on cell differentiation, tissue development and homeostasis. The family includes several interleukins, a variety of growth and colony stimulating factors, erythropoietin, leukaemia inhibitory factor, ciliary neurotrophic factor, the interferons, as well as leptin, prolactin and growth hormone. LÄS MER