Sökning: "nerve repair"

Visar resultat 1 - 5 av 74 avhandlingar innehållade orden nerve repair.

1. 1. Sutures bridging nerve defects

   Författare :Peter Scherman; Malmö Handkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; traumatology; Surgery; continuous longitudinal sutures; nerve repair; nerve regeneration; nerve defect; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : A new and simple method for the repair of nerve defects, in which sutures alone are used to guide regeneration between the nerve endings, was developed. Bilateral seven to 17 mm rat sciatic nerve defects were bridged by continuous longitudinal sutures with or without different modifications, by conventional autologous nerve grafts or direct repair under tension as controls. LÄS MER

3. 2. The sensational hand. Clinical assessment after nerve repair

   Författare :Birgitta Rosén; Malmö Handkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; substitution of senses; artificial sensibility; reliability; validity; diagnose-specific; documentation; assessment; longitudinal; functional outcome; hand; sensibility; ulnar nerve; nerve repair; median nerve; brain plasticity; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Following the transection and repair of major nerve trunks in the forearm, the functional outcome is influenced by mechanisms in the peripheral, as well as in the central nervous system. In the present thesis the interest is focused on assessment of the outcome after nerve repair, central nervous factors influencing the outcome, and sense substitution to compensate for sensory loss. LÄS MER

4. 3. Development of biosynthetic conduits for peripheral nerve repair

   Författare :Aleksandra McGrath; Liudmila N Novikova; John Haycock; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biosynthetic conduit; Mesenchymal stem cells; Nerve graft; Nerve tissue engineering; Peripheral nerve injury; Schwann cells;

   Sammanfattning : Peripheral nerve injuries are often associated with significant loss of nervous tissue leading to poor restoration of function following repair of injured nerves. Although the injury gap could be bridged by autologous nerve graft, the limited access to donor material and additional morbidity such as loss of sensation and scarring have prompted a search for biosynthetic nerve transplants. LÄS MER

5. 4. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration

   Författare :Mariann Sondell; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Schwann cell; SCG; rat; peripheral nerve regeneration; neuropilin-1; nerve repair; mouse; growth factor; flk-1; axonal outgrowth; DRG; VEGF; Animal physiology; Djurfysiologi;

   Sammanfattning : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. LÄS MER

7. 5. Repair and Reconstruction of Peripheral Nerve Injuries. Treatment with G-CSF and Stromal Vascular Fraction

   Författare :Hanna Frost; Malmö Handkirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripheral nerve injuries; nerve regeneration; reconstructive surgical procedures; diabetes mellitus; rat sciatic nerve; granulocyte colony-stimulating factor; stromal vascular fraction; electrospinning; rats; Schwann cells;

   Sammanfattning : While surgery is a cornerstone in treatment of peripheral nerve injuries, it is not a comprehensive approach, and outcome is unsatisfactory, especially sensory function. The present aim was to translate recent findings about stem- and progenitor cells to improve regenerative outcome, where the cells have to be autologous, available within the same surgical procedure, and minimally manipulated. LÄS MER