Sökning: "glial growth factor"
Visar resultat 1 - 5 av 71 avhandlingar innehållade orden glial growth factor.
1. Sensory neuronal protection & improving regeneration after peripheral nerve injury
Sammanfattning : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. LÄS MER
2. Neuronal and glial differentiation of expanded neural stem and progenitor cells; in vitro and after transplantation
Sammanfattning : In this thesis we have used cells dissected from the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the cortical primordium of the embryonic mouse forebrain. The tissue was dissected from either i) wild-type mice, ii) green fluorescent protein (GFP)-, or iii) Gtv-a-expressing transgenic mice, and subsequently grown and expanded in vitro using two different protocols. LÄS MER
3. Effects of Ischaemia on the Neuroretina and Retinal Blood Vessels
Sammanfattning : Identification of the intracellular signal transduction pathways activated in retinal ischaemia may be important in revealing novel pharmacological targets. The retinal blood vessels are key organs in circulatory failure, and in this work the retinal vasculature was therefore examined separately from the neuroretina. LÄS MER
4. Molecular factors influencing nerve growth : studies on the developing rodent trigeminal ganglion and tooth pulp
Sammanfattning : The adult tooth pulp has a rich protective sensory innervation from the trigeminal ganglion (TG). The developmental establishment of this exclusively nociceptive innervation is not fully understood today. LÄS MER
5. Neurotrophic Factor Receptors in the Normal and Injured Visual System : Focus on Retinal Ganglion Cells
Sammanfattning : The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. LÄS MER