Sökning: "position specificity"

Visar resultat 1 - 5 av 83 avhandlingar innehållade orden position specificity.

  1. 1. Haematopoietic Serine Proteases : A Cleavage Specificity Analysis

    Författare :Michael Thorpe; Lars Hellman; Urban Gullberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER

  3. 2. Contributions to the understanding of diversity and evolution in the genus Coreomyces

    Författare :Henrik Sundberg; Stefan Ekman; Åsa Kruys; Donald H. Pfister; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ascomycetes; Coreomyces; Corixidae. DNA; DNA extraction; Fungi; ge-nome; host specificity; Laboulbeniales; mating types; MAT-loci; meth-odology; NGS; parasite; position specificity; systematics; taxonomy; Biology with specialization in Systematics; Biologi med inriktning mot systematik; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Sammanfattning : The Laboulbeniales is an order of enigmatic ascomycete fungi that are obligate microscopic parasites of arthropods, which are usually non-detrimental. They typically display a high degree of host specificity, and the genus Coreomyces, which is the recurring theme of this thesis, is no exception. LÄS MER

  4. 3. Cleavage Specificity of Mast Cell Chymases

    Författare :Mattias K. Andersson; Lars Hellman; Gunnar Pejler; Per Venge; Uppsala universitet; []
    Nyckelord :Biology; Immunology; Mast cell; Serine protease; Chymase; Cleavage specificity; Phage display; Biologi;

    Sammanfattning : Mast cells (MC) are potent inflammatory cells that are known primarily for their prominent role in IgE mediated allergies. However, they also provide beneficial functions to the host, e.g. in bacterial and parasitic defence. LÄS MER

  5. 4. Lipase Specificity and Selectivity : Engineering, Kinetics and Applied Catalysis

    Författare :Mohamad Takwa; Karl Hult; Bernhard Hauer; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi;

    Sammanfattning : The specificity and selectivity of the enzyme Candida antarctica lipase B (CALB) were studiedfor several substrates and applications.With help of molecular modeling, the active site of CALB was redesigned for the ring openingpolymerization of D,D‐lactide. LÄS MER

  7. 5. Epidemiology of meniscus position: associations with knee symptoms and osteoarthritis

    Författare :Fredrik Svensson; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; meniscus position; Knee osteoarthritis; magnetic resonance imaging; Pain;

    Sammanfattning : Meniscal extrusion (ME) in the knee joint is defined as when the peripheral border of the meniscus is substantially located outside the joint margin. Prior studies have reported that ME is associated with meniscal tears, meniscal degeneration, and the presence of knee osteoarthritis (OA). LÄS MER