Sökning: "chymase"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet chymase.

  1. 1. Cleavage Specificity of Mast Cell Chymases

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mattias K. Andersson; Uppsala universitet.; [2008]
    Nyckelord :Biology; Immunology; Mast cell; Serine protease; Chymase; Cleavage specificity; Phage display; Biologi;

    Sammanfattning : Mast cells (MC) are potent inflammatory cells that are known primarily for their prominent role in IgE mediated allergies. However, they also provide beneficial functions to the host, e.g. in bacterial and parasitic defence. LÄS MER

  2. 2. Haematopoietic Serine Proteases A Cleavage Specificity Analysis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Michael Thorpe; Uppsala universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER

  3. 3. Cutting Edge – Cleavage Specificity and Biochemical Characterization of Mast Cell Serine Proteases

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ulrika Karlson; Uppsala universitet.; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; mast cell; serine protease; tryptase; chymase; substrate specificity; phage display; Biologi; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi; molekylär immunologi; Molecular Immunology;

    Sammanfattning : It is well established that mast cells (MC) are key players in airway pathologies such as allergic asthma, but they are also known to contribute to host defense and tissue remodeling. MC serine proteases are the major protein components of mast cell granules and accordingly, are most likely involved in many aspects of MC function. LÄS MER

  4. 4. Mast Cells as Sentinels Role of serglycin and mast cell proteases in infection and inflammation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ananya Roy; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mast cells; serglycin; chymase; infection; parasite; Immunologi; Immunology;

    Sammanfattning : Mast cells (MCs), normally classified into connective tissue MCs and mucosal MCs, are highly granulated cells found in the interface between the interior and the exterior environment of our body, e.g. skin, airways and gastro-intestinal tract. LÄS MER

  5. 5. Sculpted through Time Evolution and Function of Serine Proteases from the Mast Cell Chymase Locus

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Maike Gallwitz; Uppsala universitet.; [2006]
    Nyckelord :Immunology; immune system; mast cell; chymase locus; serine protease; evolution; gene duplication; Immunologi;

    Sammanfattning : Immune cells like NK cells, T cells, neutrophils and mast cells store high amounts of granule serine proteases, graspases. Graspases are encoded from the mast cell chymase locus. The human locus holds four genes: α-chymase, cathepsin G, and granzymes H and B. In contrast, the mouse locus contains at least 14 genes. LÄS MER