Sökning: "Biologi med inriktning mot evolutionär organismbiologi"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Biologi med inriktning mot evolutionär organismbiologi.

  1. 1. Hidden Diversity Revealed : Genomic, Transcriptomic and Functional Studies of Diplomonads

    Författare :Jon Jerlström-Hultqvist; Staffan Svärd; Adrian Hehl; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia intestinalis; Spironucleus salmonicida; Spironucleus barkhanus; intestinal parasite; hydrogenosome; mitosome; lateral gene transfer; horizontal gene transfer; diplomonad; metamonad; sexual recombination; transfection; protein complex purification; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : The diplomonads are a diverse group of eukaryotic microbes found in oxygen limited environments such as the intestine of animals were they may cause severe disease. Among them, the prominent human parasite Giardia intestinalis non-invasively colonizes the small intestine of humans and animals where it induces the gastrointestinal disease giardiasis. LÄS MER

  2. 2. Contributions to the understanding of diversity and evolution in the genus Coreomyces

    Författare :Henrik Sundberg; Stefan Ekman; Åsa Kruys; Donald H. Pfister; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ascomycetes; Coreomyces; Corixidae. DNA; DNA extraction; Fungi; ge-nome; host specificity; Laboulbeniales; mating types; MAT-loci; meth-odology; NGS; parasite; position specificity; systematics; taxonomy; Biology with specialization in Systematics; Biologi med inriktning mot systematik; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Sammanfattning : The Laboulbeniales is an order of enigmatic ascomycete fungi that are obligate microscopic parasites of arthropods, which are usually non-detrimental. They typically display a high degree of host specificity, and the genus Coreomyces, which is the recurring theme of this thesis, is no exception. LÄS MER

  3. 3. Translational research of the quaking gene : Focusing on the conjunction between development and disease

    Författare :Bryn Farnsworth; Lina Emilsson; Roman Chrast; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; QKI; glia; oligodendrocyte; Alzheimer s; schizophrenia; zebrafish; statistics; morpholino; Biologi med inriktning mot evolutionär organismbiologi; Biology with specialization in Evolutionary Organismal Biology;

    Sammanfattning : Quaking (QKI) is an RNA binding protein involved in the post-transcriptional regulation of gene expression. Originally identified as the cause of hypomyelination in a mouse mutant, it has since been consistently implicated in a wide range of neurological diseases. LÄS MER

  4. 4. Population genetic history and patterns of admixture : Examples from northeastern and southern Africa

    Författare :Nina Hollfelder; Mattias Jakobsson; Michele Ramsay; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; population structure; genetic admixture; genomic variation; Africa; population genomics; lactase persistence; sex-biased admixture; human evolutionary genetics; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Sammanfattning : The origin of humans lies in Africa, as has been shown by archaeology, paleontology and genetics. Here, we can find the largest genetic diversity and the deepest split among human populations. African genetic diversity has been shaped by a long and complex history. LÄS MER

  5. 5. Musculoskeletal Development in Jawed Vertebrates : Gene function, cis-regulation, and 3D phenotypes in zebrafish

    Författare :Jake Leyhr; Tatjana Haitina; Sophie Sanchez; Per Ahlberg; Chrissy Hammond; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nkx3.2; Gdf5; Mkx; zebrafish; jaw joint; skeleton; fin development; cartilage; tendon; ligament; enhancer; CRISPR Cas9; mutant; microCT; synchrotron; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Sammanfattning : Vertebrate skeletons are an intricate framework of bony and cartilaginous structures that form through carefully orchestrated developmental processes, guided by interacting genetic pathways that regulate cellular differentiation, migration, and tissue morphogenesis. The specific timing and localisation of gene expression shapes the diverse array of skeletal elements, from the flexible cartilages of the embryonic stage to the hardened bones that provide structural support in adulthood, and the joints and connective tissues that articulate the musculoskeletal system. LÄS MER