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6. Natural Products from Cameroonian Medicinal Plants
Sammanfattning : Natural product chemistry is a main research area in Cameroon, as well as for the division of Bioorganic Chemistry at Lund Institute of Technology. A review of the results obtained recently with Cameroonian medicinal plants shows that a large number of compounds, many with complex structures, have been isolated and characterised, and the work presented in this thesis is part of this effort. LÄS MER
7. The role of rodents in the transmission of Echinococcus multilocularis and other tapeworms in a low endemic area
Sammanfattning : Echinococcus multilocularis is zoonotic tapeworm in the Taeniidae family with a two part lifecycle involving a canid definitive host and a rodent intermediate host. The work of this thesis followed the first identification E. multilocularis in Sweden in 2011 in a red fox (Vulpes vulpes). LÄS MER
8. On the role of Natural Killer cell immunogenetics for the outcome of immunotherapy in acute myeloid leukemia
Sammanfattning : Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in myeloid leukemias. Thus, understanding NK cell-related biomarkers that influence clinical outcome are warranted. LÄS MER
9. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota
Sammanfattning : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. LÄS MER
10. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes
Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER