Sökning: "hepatic steatosis"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden hepatic steatosis.

  1. 1. Liver tissue characterization and influence of chemotherapy in liver surgery

    Författare :Jan Nilsson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal liver metastases; liver regeneration; incisional hernia; steatosis; hepatic microcirculation; diffuse reflectance spectroscopy; DRS; sidestream dark-field imaging; SDF; laser speckle contrast imaging; LSCI;

    Sammanfattning : Background & Aims: Primary liver cancer is the second most common cause of death from cancer worldwide. In the western world, the majority of liver malignancies consist of colorectal metastases. Liver resection is the primary treatment for cure in liver tumor disease. LÄS MER

  2. 2. Role of cholesterol metabolism in hepatic steatosis and glucose tolerance

    Författare :Osman Salih Osman Ahmed; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The liver is the central organ for lipid, lipoprotein and glucose homeostasis, thus hepatic metabolic disturbances can predispose individuals to develop cardiometabolic disorders (CMD) such as atherosclerotic cardiovascular diseases (ASCVD), type 2 diabetes mellitus (T2DM), and nonalcoholic fatty liver disease (NAFLD).The overall aim of this thesis was to expand the knowledge on how genetic and pharmacological interventions on hepatic and intestinal cholesterol metabolism could affect the pathophysiology of CMD. LÄS MER

  3. 3. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota

    Författare :Lovisa Heyman; Molekylär nutrition; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; obesity; type 2 diabetes; berries; low-grade inflammation; gut microbiota; hepatic steatosis; gene expression; DNA methylation; lingonberry; blackcurrant; bilberry; açai;

    Sammanfattning : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. LÄS MER

  4. 4. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease

    Författare :Marie Byenfeldt; Anders Elvin; Per Fransson; Odd Helge Gilja; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometric measurement; diagnostic imaging; elasticity imaging technique; blood supply; BMI; body position; fatty liver; liver disease; hepatic steatosis; liver fibrosis; liver stiffness; obesity; postural change; pressure; probe; sex characteristic; shear wave elastography; skin-to-liver capsule distance; transducer and ultrasonography; Radiography; radiografi;

    Sammanfattning : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. LÄS MER

  5. 5. LXR regulation of hepatic gene expression and pituitary dependent hormones

    Författare :Pia Kotokorpi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Liver X receptor; growth hormone; gene regulation; metabolism; hepatocyte; hepatic steatosis; species differences;

    Sammanfattning : The liver X receptors (LXRs) are ligand activated transcription factors involved in the regulation of metabolic genes. LXRs are considered potential drug targets to treat metabolic disorders, however, unwanted side effects, as revealed from rodent studies, include increased lipogenesis in the liver and increased plasma triglyceride levels. LÄS MER